Evidence map›Paper›PMID 40598048›Full record

ArticleBMC medical education2025

Educating tomorrow's donors: a high school initiative to promote blood and stem cell donation through stem education.

Katia Mareschi, Alessia Giovanna Santa Banche Niclot, Elena Marini, Camilla Francesca Proto, Federico Divincenzo, Claudia Peirolo, Giulia Zucchetti, Franca Fagioli

Abstract read
In one paragraph

Article in BMC medical education, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katia MareschiDepartment of Public Health and Paediatrics, University of Turin, Piazza Polonia 94, Turin, 10126, Italy. katia.mareschi@unito.it.
Alessia Giovanna Santa Banche NiclotDepartment of Public Health and Paediatrics, University of Turin, Piazza Polonia 94, Turin, 10126, Italy.
Elena MariniDepartment of Public Health and Paediatrics, University of Turin, Piazza Polonia 94, Turin, 10126, Italy.
Camilla Francesca ProtoPaediatric Onco-Haematology Division, Regina Margherita Childrens' Hospital, City of Health and Science of Turin, Turin, 10126, Italy.
Federico DivincenzoDepartment of Public Health and Paediatrics, University of Turin, Piazza Polonia 94, Turin, 10126, Italy.
Claudia PeiroloPaediatric Onco-Haematology Division, Regina Margherita Childrens' Hospital, City of Health and Science of Turin, Turin, 10126, Italy.
Giulia ZucchettiPaediatric Onco-Haematology Division, Regina Margherita Childrens' Hospital, City of Health and Science of Turin, Turin, 10126, Italy.
Franca FagioliDepartment of Public Health and Paediatrics, University of Turin, Piazza Polonia 94, Turin, 10126, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHematopoietic stem cell transplantation (HSCT) is a life-saving procedure for pediatric patients with hematologic malignancies, genetic disorders, and other serious conditions. However, its success critically depends on the availability of compatible donors, which remains a challenge-especially in ethnically homogeneous populations. Raising awareness among adolescents may help expand donor registries and promote civic engagement in public health.

methodsThis study, conducted by the Pediatric Onco-Hematology team at an Italian University, aimed to bridge the gap in donor awareness among adolescents by implementing an educational intervention to increase knowledge about blood diseases, stem cell donation, and the donor registration process. The intervention, which targeted high school students, sought to foster informed decision-making and encourage future blood and stem cell donors. The program involved 900 students (aged 16-18) from 12 scientific-track schools. Designed in collaboration with school staff and aligned with national curricular guidelines in biology and civic education, the intervention included 2-h scientific seminars and observation-based visits to a Children's Hospital transplant center. A 10-item post-intervention Likert-scale questionnaire assessed seminar clarity, student engagement, understanding of donation processes, satisfaction with the presenter, and willingness to register as donors. Two open-ended questions invited qualitative feedback. Data were analyzed using descriptive statistics and thematic analysis.

resultsA total of 346 students completed the survey. Quantitative data showed high levels of satisfaction and increased awareness of blood and stem cell donation. Many students expressed interest in future donor registration and biomedical career paths. Thematic analysis of open-ended responses revealed strong appreciation for real-world laboratory exposure, clarity of scientific content, and the motivational impact of learning about donation. No pre-intervention survey was conducted, which limits comparisons.

conclusionsThe program effectively promoted awareness of blood and stem cell donation among adolescents and stimulated interest in STEM-related careers. Given its structured and adaptable format, this model could be implemented in other educational contexts to enhance health literacy and support donor recruitment efforts. Future editions will include pre-post evaluation and longitudinal tracking to assess sustained impact.

Indexed as

Blood DonorsHematopoietic Stem Cell TransplantationAdolescentFemaleHealth Knowledge, Attitudes, PracticeHumansItalyMaleSchoolsStudentsSurveys and QuestionnairesAdolescentsDonationEducationHematopoietic stem cell transplantationHigh school

Identifiers

PMID40598048
PMCPMC12220465

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.