ArticleBMC psychiatry2025
The association of age of onset on suicide attempts in patients with chronic schizophrenia: a cross-sectional study.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Untargeted plasma metabolomics identifies metabolite signatures associated with suicidality status in chronic schizophrenia.European archives of psychiatry and clinical neuroscience · 2026Article
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4 authors.
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Abstract
backgroundThere are differences in some clinical symptoms among patients with schizophrenia at different ages of onset. However, the association of age at onset on the prevalence and associated factors of suicide attempts in schizophrenia is still unclear.
methodsA total of 949 patients with chronic schizophrenia in stable phase were enrolled. The onset of schizophrenia at or before age of 25 years was regarded as youth-onset (YO), and the onset after age of 25 years was regarded as non-youth-onset (NYO). Insomnia Severity Index (ISI), Positive and Negative Syndrome Scale (PANSS), Interpersonal Reactivity Index (IRI), Toronto Alexithymia Scale (TAS), Mini-mental State Examination (MMSE), and Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) were used to assess insomnia, psychotic symptoms, empathy, narration, and cognitive abilities of the subjects, respectively.
resultsThere was no significant difference in the prevalence of suicide attempts between patients with YO and NYO (P > 0.05). Among YO patients, those with suicide attempts had significantly higher PANSS total scores, positive factor scores, excitability/hostility factor scores, and depression/anxiety factor scores (all P < 0.001), with the positive factor scores (P < 0.001, β = 0.18, OR = 1.19, 95%CI:1.10-1.30) and depression/anxiety factor scores (P < 0.001, β = 0.23, OR = 1.26, 95%CI:1.13-1.41) being independent risk factors for suicide attempts. However, the risk of suicide attempts in NYO patients was not significantly correlated with these factors.
conclusionsThere was no significant difference in the prevalence of suicide attempts between YO and NYO schizophrenic patients, whereas there was a significant difference in their associated influencing factors.
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