Evidence map›Paper›PMID 40597993›Full record

ArticleBMC psychiatry2025

Acute suicidal ideation in context: highlighting sentiment-based markers through the diary entries of a clinically depressed sample.

Damien Lekkas, Amanda C Collins, Michael V Heinz, Tess Z Griffin, Arvind Pillai, Subigya K Nepal, Daniel M Mackin, Andrew T Campbell, Nicholas C Jacobson

Abstract read
In one paragraph

Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Damien LekkasCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA. Damien.Lekkas.GR@dartmouth.edu.ORCID https://orcid.org/0000-0002-6995-9223
Amanda C CollinsCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0002-8258-2272
Michael V HeinzCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0003-0866-0508
Tess Z GriffinCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0001-5462-575X
Arvind PillaiDepartment of Computer Science, Dartmouth College, Hanover, NH, USA.ORCID https://orcid.org/0000-0002-2489-1130
Subigya K NepalDepartment of Computer Science, Dartmouth College, Hanover, NH, USA.ORCID https://orcid.org/0000-0002-4314-9505
Daniel M MackinCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0002-2188-2968
Andrew T CampbellCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0001-7394-7682
Nicholas C JacobsonCenter for Technology and Behavioral Health, Geisel School of Medicine, Dartmouth College, 46 Centerra Parkway, Suite 300, Lebanon, 03766, NH, USA.ORCID https://orcid.org/0000-0002-8832-4741

Funding

Personalized Deep Learning Models of Rapid Changes in Major Depressive Disorder Symptoms using Passive Sensor Data from Smartphones and Wearable DevicesR01MH123482 · NIMH · DARTMOUTH COLLEGE · PI JACOBSON, NICHOLAS CHARLES · 2020 to 2024
$2.6M
NIDA NIH HHS 5P30DA02992610NIMH NIH HHS R01 MH123482NIMH NIH HHS R01MH123482
6 · The paper itself

Abstract

backgroundDespite major strides in conceptualizing and modeling the multifaceted nature of suicidal thought and behavior (STB) over the past few decades, the overall predictability of STB has not improved. This may be partly due to the dynamic nature of suicidal ideation (SI), which often fluctuates over hours, yet is largely overlooked in studies. Bolstered by the application and promise of natural language processing (NLP) across the mental health field, efforts toward richer operationalization of acute SI may include analyses on written data that occur alongside changes in SI, thus offering a better understanding of STB as it unfolds.

methodsEcological momentary assessment (EMA) data from 268 participants with major depressive disorder (MDD) were utilized to investigate acute changes in SI. Data consisted of thrice-daily SI severity scores measured through self-report responses to item 9 of the Patient Health Questionnaire mobile version (MPHQ-9) as well as free-form diary text. Using difference scores and probability of acute change thresholds, eleven acute SI phase trajectory types were defined to label change in SI over three consecutive EMAs. In total, 5,938 acute SI trajectories were paired with the temporally centered diary entries. The Sentiment Analysis and Cognition Engine (SEANCE) tool was applied to quantify the written content of each diary entry across eight established lexica. Entry results were grouped based on phase trajectory type, and the Kruskal-Wallis test was employed with post-hoc multiple hypothesis correction to statistically compare SEANCE features between all group pairs.

resultsThere were 131 statistically significant (adjusted p-value < 0.05) pairwise differences between acute SI phase trajectory groups, implicating 31 NLP features. Consistent with the literature, results highlighted qualities of writing that are generally associated with heightened SI, including personal pronoun usage, passivity, and negative valence. Patterns of significance also uncovered novel contextual nuance in terms of how characteristics such as verbosity, hostility, anger, and pleasantness present in relation to SI over short change trajectories.

conclusionsThis work provides an accessible exploratory framework that capitalizes on the benefits of dense EMA sampling and NLP to profile and quantify acute SI trajectories. The use of the MPHQ's item 9 to quantify SI is an important limitation as it is designed to also capture precursory SI, passive SI, and SI-adjacent behaviors, potentially overestimating the SI expressed by participants. Nonetheless, future research should continue to focus on short timeframes as there are likely important signals and interpretative nuances to SI expression that have yet to be fully detailed.

Indexed as

Ecological Momentary AssessmentMajor Depressive DisorderNatural Language ProcessingSuicidal IdeationAdultFemaleHumansMaleMiddle AgedYoung AdultAcute suicidal ideationEcological momentary assessmentFree-text responseLexiconNatural Language processingSentiment analysis

Identifiers

PMID40597993
PMCPMC12220180

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.