Trial reportBMC psychiatry2025
Analysis of the impact of dexmedetomidine on the vital signs of patients with anxiety at various time intervals upon entering the operating room.
Trial report in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 1 synthesis or guideline pooled it.
- The anxiolytic effect of dexmedetomidine in adult perioperative patients: a systematic review with meta-analysis of randomized controlled trials.Frontiers in psychiatry · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveInvestigating preoperative anxiety and its determinants among patients with gastrointestinal tumors, and assessing the efficacy of dexmedetomidine in improving vital signs among patients with moderate to severe anxiety.
methodsA total of 100 patients scheduled for elective laparoscopic gastrointestinal tumor resection were included in the study. Preoperative data were collected, and anxiety levels were assessed. Patients with moderate to severe anxiety were randomly assigned to one of three groups: regular-dose dexmedetomidine (Group D1), low-dose dexmedetomidine (Group D2), and control (Group C). The systolic blood pressure, diastolic blood pressure, and heart rate of patients in all three groups were compared at four different time points: upon entering the operating room (T0), during arterial puncture needle insertion (T1), during anesthesia induction (T2), and upon successful insertion of the endotracheal tube (T3).
resultsThe average GAD-7 score among patients was 11.01 ± 3.710, and it correlated with age, level of education, and occupation (P < 0.05). Patients with moderate to severe anxiety upon entering the operating room exhibited higher systolic blood pressure, diastolic blood pressure, and heart rate compared to those with mild anxiety (P < 0.05). Compared to Group C, both Groups D1 and D2 showed similar systolic blood pressure, diastolic blood pressure, and heart rate at the T0 time point (P > 0.05). However, their systolic blood pressure, diastolic blood pressure, and heart rate at time points T1, T2, and T3 were lower than those of Group C (P < 0.05).
conclusionPreoperative anxiety levels of patients with gastrointestinal tumors are associated with age, educational background, and occupation. Patients experiencing moderate to severe anxiety tend to exhibit elevated blood pressure and increased heart rate upon entering the operating room. Administering a low dose of dexmedetomidine has been observed to improve the vital signs of such patients with anxiety during arterial puncture and catheterization, anesthesia induction, and tracheal intubation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.