Evidence map›Paper›PMID 40597949›Full record

ArticleBMC cancer2025

Evaluation of 30-day mortality rate following intravenous systemic anticancer therapy: a retrospective analysis.

Taha Enes Cetin, Osman Sutcuoglu, Orhun Akdogan, Gozde Savas, Nazan Günel, Aytug Uner, Nuriye Ozdemir, Ahmet Ozet, Ozan Yazici

Abstract read
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Wearable-derived postdischarge mobility as a digital biomarker for 90-day readmission and mortality in metastatic cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  2. Search for prognostic markers of mortality in inpatients receiving palliative chemotherapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taha Enes CetinDepartment of Internal Medicine, Gazi University, Ankara, Turkey.
Osman SutcuogluDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Orhun AkdoganDepartment of Medical Oncology, Gazi University, Ankara, Turkey. orhunakdogan@gmail.com.
Gozde SavasDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Nazan GünelDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Aytug UnerDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Nuriye OzdemirDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Ahmet OzetDepartment of Medical Oncology, Gazi University, Ankara, Turkey.
Ozan YaziciDepartment of Medical Oncology, Gazi University, Ankara, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThis study aims to determine the 30-day mortality rate following intravenous systemic anticancer therapies (SACT) and to compare mortality rates between different therapeutic modalities, including immunotherapy, monoclonal antibodies, and chemotherapy. MATERIALS AND

methodsA retrospective analysis was conducted on cancer patients who received intravenous SACT between January 1, 2022, and December 31, 2022. Patient data, including demographics, cancer types, treatment details, and mortality outcomes, were collected from hospital records. The primary endpoint was 30-day mortality following the last dose of SACT.

resultsAmong the 1,937 patients included, the overall 30-day mortality rate post-SACT was 7%. Significant factors affecting 30-day mortality included Eastern Cooperative Oncology Group (ECOG) performance status, body mass index (BMI), and smoking status. In Non-Stage 4 treated patients, a higher ECOG score was significantly associated with increased mortality. In Stage 4 treated patients, both a higher ECOG score and a lower BMI were independent predictors of increased mortality. Additionally, receiving Stage 4 treatment and being an active smoker significantly increased mortality risk in patients with gastrointestinal and breast cancers.

conclusionMonitoring 30-day mortality post-SACT is essential for improving oncological care quality. Identifying and addressing modifiable risk factors and carefully selecting patients for modern oncological treatments can help reduce mortality rates. Further prospective studies are warranted to explore the impact of immunotherapy on short-term mortality in diverse cancer populations.

Indexed as

Antineoplastic AgentsNeoplasmsAdministration, IntravenousAdultAgedAged, 80 and overFemaleHumansImmunotherapyMaleMiddle AgedRetrospective StudiesRisk FactorsAntineoplastic Agents

Identifiers

PMID40597949
PMCPMC12210842

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.