Evidence map›Paper›PMID 40597895›Full record

ArticleBMC nephrology2025

The association of Malnutrition-Inflammation Score with sleep quality and mental health in hemodialysis patients: a multicenter cross-sectional study.

Mehrnaz Morvaridi, Hossein Bavi Behbahani, Meysam Alipour, Ahmad Zare Javid, Sara Keramatzadeh, Shiva Shokri, Pardis Tofighzadeh, Fatemeh Fayazfar, Haleh Soltaniyan Dehkordi, Elahe Ghadimi and 2 more

Abstract readMulticenter Study
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Mehrnaz MorvaridiDepartment of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
Hossein Bavi BehbahaniDepartment of Nutrition, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran. hosseinbbehbahani@gmail.com.
Meysam AlipourDepartment of Nutrition, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Ahmad Zare JavidNutrition and Metabolic Diseases Research Center Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Sara KeramatzadehStudent Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Shiva ShokriStudent Research Committee, School of Nutrition and Food Sciences, Shiraz University of Medical Science, Shiraz, Iran.
Pardis TofighzadehStudent Research Committee, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Fatemeh FayazfarStudent Research Committee, School of Nutrition and Food Sciences, Shiraz University of Medical Science, Shiraz, Iran.
Haleh Soltaniyan DehkordiStudent Research Committee, Shoushtar Faculty of Medical Sciences, Shoushtar, Iran.
Elahe GhadimiNutrition and Metabolic Diseases Research Center Clinical Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Siavash Babajafari EsfandabadNutrition Research Center, School of Nutrition and Food Science, Shiraz University of Medical Science, Shiraz, Iran.
Shokouh ShayanpourDepartment of Internal Medicine, Chronic Renal Failure Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHemodialysis is crucial for individuals with end-stage renal disease (ESRD), but it poses challenges that impact health and quality of life. Malnutrition, inflammation, sleep disturbances, and mental health disorders are common among hemodialysis patients, interconnecting and influencing outcomes. Therefore, the study aimed to investigate the association between the Malnutrition-Inflammation Score (MIS) and various health parameters, including sleep quality and mental health in hemodialysis patients.

methodsA multicenter cross-sectional study investigated the association between the MIS and health parameters in 423 hemodialysis patients across eight centers. Assessments included MIS, physical activity levels, dietary intake, sleep quality, and mental health status, along with biochemical parameters. Statistical analyses using SPSS software were conducted to identify associations.

resultsSignificant differences were observed in demographic, clinical, and biochemical characteristics across MIS quartiles (p < .05). Older age, lower BMI, longer dialysis vintage, and altered biochemical profiles were noted in higher MIS quartiles. Depression scores were significantly higher in higher MIS quartiles (p = .04). Multivariable analyses confirmed these associations, indicating higher odds of poorer sleep quality, depression, and anxiety with increasing MIS quartiles (p < .05).

conclusionThe study highlights the intricate association between malnutrition, inflammation, sleep quality, and mental health conditions in hemodialysis patients. Addressing these factors comprehensively and tailoring interventions may lead to improved outcomes and well-being.

Indexed as

InflammationKidney Failure, ChronicMalnutritionMental HealthRenal DialysisSleep QualityAdultAgedCross-Sectional StudiesDepressionFemaleHumansMaleMiddle AgedSleep Wake DisordersHemodialysisInflammationMalnutritionMental healthSleep quality

Identifiers

PMID40597895
PMCPMC12210551

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.