Evidence map›Paper›PMID 40597863›Full record

ArticleBMC cancer2025

Assessment of intra-fractional and inter-fractional motion in esophageal cancer treated with intensity-modulated proton therapy.

Xiaoying Fan, Shuting Wang, Weijie Li, Kangning Meng, Wei Huang, Yong Yin, Tianyuan Dai

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xiaoying FanDepartment of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Shuting WangDepartment of Graduate, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Weijie LiDepartment of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Kangning MengDepartment of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Wei HuangDepartment of Radiation Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China.
Yong YinDepartment of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China. yinyongsd@126.com.
Tianyuan DaiDepartment of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University, Shandong Academy of Medical Sciences, Jinan, China. daitianyuan1992@163.com.

Funding

National Natural Science Foundation of China 12105160National Natural Science Foundation of China 82072094Shandong Province Higher Education Institutions Youth Innovation Team Development Plan 2024KJJ013Shandong Provincial Natural Science Foundation ZR2019LZL017Shandong Provincial Natural Science Foundation ZR2021QA099Taishan Scholars Project of Shandong Province ts201712098Tumor precision radiotherapy peak plan 2021HZ81Xinjiang Uygur Autonomous Region key research and development project 2022B03019-5Young Talent of Lifting engineering for Science and Technology in Shandong, China SDAST2024QTB034
6 · The paper itself

Abstract

proposeProton therapy of esophageal cancer is beneficial to spare normal tissue in clinical practice. However, intra-fractional and inter-fractional variance of tumor motion during treatment may compromise target coverage. The purpose of this study was to investigate the interplay effect due to intra-fractional motion and the effect of the robust optimization parameters for inter-fractional motion in the intensity modulation proton therapy (IMPT). MATERIALS AND

methodsThis study retrospectively analyzed 42 patients with esophageal cancer treated at Shandong Cancer Hospital. The patients were divided into two groups. Twenty-one patients had a 4DCT image with 10 respiratory phases reconstructed (G

resultsFor G

conclusionIn this study, the differences in dose distributions between the 4DDD and nominal plans for G

Indexed as

Esophageal NeoplasmsProton TherapyRadiotherapy, Intensity-ModulatedAgedDose Fractionation, RadiationFemaleFour-Dimensional Computed TomographyHumansMaleMiddle AgedRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRespirationRetrospective Studies4D dynamic doseEsophageal cancerIntensity modulated proton therapyInter-fractional motionInterplay effect

Identifiers

PMID40597863
PMCPMC12211713

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.