Evidence map›Paper›PMID 40597859›Full record

ArticleBMC nephrology2025

Prevalence of chronic kidney disease in France - The constances cohort.

Jacques Blacher, Sofiane Kab, Lynda Cheddani, Jean-Michel Halimi, Bénédicte Stengel, Natalia Alencar De Pinho, Marcel Goldberg, Marie Zins, Valérie Olié

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jacques BlacherUnité hypertension artérielle, prévention et thérapeutiques cardiovasculaires, Centre de diagnostic et de thérapeutique, Hôtel- Dieu, Assistance Publique Hôpitaux de Paris, Place du Parvis Notre-Dame, Paris, 75004, France. jacques.blacher@aphp.fr.ORCID 0000-0003-4860-4279
Sofiane KabUniversité Paris Cité, "Population-based Cohorts Unit", INSERM, Paris Saclay University, UVSQ, Paris, UMS 011, France.
Lynda CheddaniUnité hypertension artérielle, prévention et thérapeutiques cardiovasculaires, Centre de diagnostic et de thérapeutique, Hôtel- Dieu, Assistance Publique Hôpitaux de Paris, Place du Parvis Notre-Dame, Paris, 75004, France.
Jean-Michel HalimiService de néphrologie-hypertension, dialyses, transplantation rénale, Hôpital Bretonneau et Hôpital Clocheville, Tours, France.
Bénédicte StengelCentre de recherche en Epidémiologie et Santé des Populations (CESP), Equipe Epidémiologie Clinique, INSERM, Université Paris Saclay, Villejuif, France.
Natalia Alencar De PinhoCentre de recherche en Epidémiologie et Santé des Populations (CESP), Equipe Epidémiologie Clinique, INSERM, Université Paris Saclay, Villejuif, France.
Marcel GoldbergUniversité Paris Cité, "Population-based Cohorts Unit", INSERM, Paris Saclay University, UVSQ, Paris, UMS 011, France.
Marie ZinsUniversité Paris Cité, Paris, France.
Valérie OliéSanté Publique France, Direction des maladies non transmissibles et traumatismes, Saint Maurice, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevention and early detection of chronic kidney disease (CKD) are major public health goals to prevent and slow its progression to kidney failure. In this respect, our main objective was to estimate the prevalence of CKD (stages 1 to 5 without replacement therapy) in French adults and to study its determinants.

methodsConstances is a population-based cohort designed as a national research infrastructure. Eligible population included participants (18-69 years) who had both isotope dilution mass spectrometry (IDMS) traceable creatinine-based estimated glomerular filration rate (eGFR) and urinary albumin-creatinine ratio measurements. Multivariable analysis was performed to assess the association between covariables of interest and CKD.

resultsOf the 11,429 subjects included in our sample, (48% women; mean (± standard deviation) age: 52 ± 13 years), 715 have CKD (ACR ≥ 3 mg/mmol creatinine and/or eGFR < 60 mL/min per 1.73 m

conclusionsOur large population-based cohort estimated that 6.3% of individuals had CKD. The majority of subjects with CKD had increased albuminuria without decreased eGFR. Albuminuria should be assessed more frequently in order to detect CKD earlier and to implement preventive treatments, especially in selected populations at risk of CKD. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Renal Insufficiency, ChronicAdolescentAdultAgedAlbuminuriaCohort StudiesCreatinineFemaleFranceGlomerular Filtration RateHumansMaleMiddle AgedPrevalenceRisk FactorsYoung AdultCreatinineAlbuminuriaChronic kidney diseaseFrancePrevalence

Identifiers

PMID40597859
PMCPMC12210490

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.