Evidence map›Paper›PMID 40597838›Full record

ArticleBMC nephrology2025

Exploring the quality of life of end-stage kidney disease patients in Khartoum State, Sudan: a multicenter cross-sectional study.

Hiba Ali Elzaki Hajomer, Osama Ahmed Elkhidir, Sara Elawad, Ahmed Balla M Ahmed, Shaima Omer Mohamed Elawad, Mohamed H Elbadawi, Wael Atif Fadl Elhassan, Rafa Awad Gasimelseed Mohamed, Kamil Merghani Ali, Tahani Amin Mahmoud and 1 more

Abstract readMulticenter Study
In one paragraph

Article in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hiba Ali Elzaki HajomerCommunity Medicine Department, National University, Khartoum, Sudan.
Osama Ahmed ElkhidirCommunity Medicine Department, National University, Khartoum, Sudan.
Sara ElawadFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan.
Ahmed Balla M AhmedFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan. m.salahballa@gmail.com.
Shaima Omer Mohamed ElawadFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan.
Mohamed H ElbadawiFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan.
Wael Atif Fadl ElhassanFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan.
Rafa Awad Gasimelseed MohamedFaculty of Medicine, University of Khartoum, Al-Qasr Street, PO Box: 102, Khartoum, 11111, Sudan.
Kamil Merghani AliCommunity Medicine Department, University of Khartoum, Khartoum, Sudan.
Tahani Amin MahmoudNational University, Khartoum, Sudan.
Sarra Mohamed KheirRoyal College of Physicians, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven the rising incidence of end-stage kidney disease (ESKD) in Sudan, assessing health-related quality of life (HRQOL) is critical for evaluating patient outcomes. This study evaluated HRQOL and associated factors in end-stage kidney disease patients in Khartoum State renal centers in Sudan.

methodsThis cross-sectional study administered the Kidney Disease Quality of Life Short Form (KDQOL-SF™) to 150 ESKD patients on maintenance dialysis for ≥ one month across 13 renal centers in Khartoum State. Data were analyzed using SPSS Statistics. Independent t-tests, ANOVA, Pearson correlation, and multiple regression analyses were conducted to assess associations. The p-value was set at 0.05 for statistical significance.

resultsThe Physical (40.17 ± 9.01) and Mental (47.10 ± 9.86) Component scores significantly affected HRQOL in ESKD patients. The lowest scores were observed for burden of kidney disease (31.25 ± 38) and work status (0.00 ± 50). The SF-12 Physical Component was associated with employment status (p < 0.001) and dialysis accompaniment (p = 0.011). Diabetes comorbidity affected the Mental Component (p = 0.017). Hospitalization frequency showed significant negative correlations with the SF-12 Mental Component (r = -0.249), burden of kidney disease (r = -0.330), effects of kidney disease (r = -0.303), and Kidney Disease Component Summary (r = -0.247). In the multiple regression model for the SF-12 Physical Component, age group was the only significant factor (p = 0.023).

conclusionBoth physical and mental health domains were significantly impaired in the studied ESKD population. The lowest scores were observed for disease burden and work status. Enhancing healthcare access, addressing comorbidities, and reducing financial strain may improve outcomes. Further longitudinal and case-control studies are warranted to clarify determinants of HRQOL.

Indexed as

Kidney Failure, ChronicQuality of LifeAdultComorbidityCross-Sectional StudiesFemaleHumansMaleMiddle AgedRenal DialysisSudanDialysisEnd-stage kidney diseaseHealth-related quality of lifeKDQOL-SF™Sudan

Identifiers

PMID40597838
PMCPMC12218816

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.