Evidence map›Paper›PMID 40597826›Full record

ArticleBMC ophthalmology2025

Investigation of anterior segment and pupillometry changes with Sirius corneal topography in chronic smokers.

Ramazan Birgul, Ahmet Kursad Sakallioglu

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ramazan BirgulDepartment of Ophthalmology, Izmir City Hospital, Izmir, Turkey. ramazanbirgul@hotmail.com.ORCID http://orcid.org/0000-0001-5097-3087
Ahmet Kursad SakalliogluDepartment of Ophthalmology, Trakya University Medical Faculty Hospital, Edirne, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic smoking is still one of the world's leading health problems. In addition to the systemic effects of cigarette smoking, ocular effects are also present, as ocular structures are a mucosal surface. The aim of this study was to investigate the effects of chronic cigarette smoking on the anterior segment and pupil using Sirius corneal topography. MATERIALS AND

methodsThe study included 70 chronic smokers in the experimental group and 72 non-smokers in the control group. Central corneal thickness (CCT); corneal volume (CV); anterior chamber depth (ACD); anterior chamber angle (ACA); anterior chamber volume (ACV); first non-contact tear breakup time (NCTBUT); mean NCTBUT; meibography; scotopic, mesopic and photopic pupil sizes; and dynamic pupil sizes at 0, 1, 2, 4, 6, 8 and 10 s were measured.

resultsThere were no statistically significant differences between the chronic smoker group and the control group in terms of age; gender; CCT; CV; ACD; ACA; ACV; first NCTBUT; mean NCTBUT; and dynamic pupillometry at 2, 4, 6, 8 and 10 s. There were statistically significant differences between the groups in terms of meibography; scotopic, mesopic and photopic static pupillometry; and dynamic pupillometry at 0 and 1 s.

conclusionIn this study, only the meibomian gland was affected among the anterior segment structures. Changes in other anterior segment structures were not significant. On the pupil, chronic smoking increased the scotopic, mesopic and photopic pupil diameter and the early stages of dynamic pupillometry. In addition CV; ACD; ACA; ACV; first NCTBUT; mean NCTBUT; and dynamic pupillometry are important in terms of being the first literature in which they were evaluated.

Indexed as

Anterior Eye SegmentCorneal TopographyPupilSmokingAdultCorneaFemaleHumansMaleMiddle AgedAnterior segmentCigarettePupilSirius corneal topography

Identifiers

PMID40597826
PMCPMC12220193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.