Evidence map›Paper›PMID 40597745›Full record

SynthesisBMC infectious diseases2025

Prevalence of chronic kidney diseases among people living with HIV in Ethiopia: a systematic review and meta-analysis.

Bruktawit Eshetu, Alemu Gedefie, Zewudu Mulatie, Ermiyas Alemayehu, Melaku Ashagrie Belete, Saba Gebremichael Tekele, Daniel Gebretsadik Weldehanna, Hussen Ebrahim, Mihret Tilahun, Habtu Debash and 2 more

Abstract readSystematic ReviewMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Bruktawit EshetuDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia. bruktieshetu1989@gmail.com.
Alemu GedefieDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Zewudu MulatieDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Ermiyas AlemayehuDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Melaku Ashagrie BeleteDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Saba Gebremichael TekeleDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Daniel Gebretsadik WeldehannaDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Hussen EbrahimDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Mihret TilahunDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Habtu DebashDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Agumas ShibabewDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.
Ousman MohammedDepartment of Medical Laboratory Sciences, College of Medicine and Health Sciences, Wollo University, P.o.box:1145, Dessie, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is a common condition among people living with HIV worldwide, but it is more common in patients from Africa. Both opportunistic infections and chronic illnesses are responsible for a large proportion of people living with HIV in low-resource settings like Ethiopia, which are linked to higher rates of morbidity and mortality. Further, as CKD is acknowledged as a major global public health issue affecting productivity, health, and healthcare costs, the goal of this systematic review and meta-analysis was to ascertain the pooled prevalence of CKD among people living with HIV in Ethiopia.

methodsThe Preferred Reporting Items for Systematic Reviews and Meta-Analysis criteria were followed by us when we carried out a systematic review and meta-analysis. Electronic databases like PubMed, Google Scholar, African Journal Online, Science Direct, Embase, Research Gate, Scopus, and Web of Sciences were searched in order to find pertinent articles. Domain-based assessment was used to evaluate the listed studies' quality. Stata version 14.0 software was used to conduct the statistical analysis. We used the Cochran's Q test and I

resultsThis systematic review and meta-analysis included 12 articles from Ethiopia, and 3364 People living with HIV were included. The overall pooled prevalence of chronic kidney disease (CKD) among People living with HIV in Ethiopia was 18.10% (95% CI: 14.17-22.03). According to the CKD calculation, the pooled prevalence of CKD was 18.06 (95% CI: 10.62-25.49) by using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) formula and 18.38 (95% CI: 15.75-21.02) by using the Modification of Diet in Renal Diseases (MDRD) formula. Using random-effect model, the I

conclusionPeople living with HIV had a high prevalence of CKD, according to this systematic review and meta-analysis. Consequently, frequent CKD diagnosis at baseline, antiretroviral therapy follow-up and screening improves the quality of life for People living with HIV. SYSTEMATIC REVIEW REGISTRATION: PROSPERO (2023: CRD42023431245).

Indexed as

HIV InfectionsRenal Insufficiency, ChronicEthiopiaFemaleHumansPrevalenceChronic kidney diseaseEthiopiaMeta-analysisPeople living with HIVPrevalenceSystematic review

Identifiers

PMID40597745
PMCPMC12219290

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.