ArticleBMC gastroenterology2025
The influence of subjective well-being on anxiety, depression and quality of life in patients with functional dyspepsia.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Cyberchondria, Psychological Well-Being, Anxiety, and Depression Levels in Female Patients with Irritable Bowel Syndrome.Medicina (Kaunas, Lithuania) · 2026Article
- Associations between psychological factors and functional dyspepsia symptoms with consideration of gender differences.Scientific reports · 2026Article
- Gastric cancer secondary prevention in dyspeptic patients.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- Mental Health Promotion Through Nursing Interventions Focused on Anxiety, Sleep and Well-Being: A Scoping Review.International journal of mental health nursing · 2026Article
- Factors influencing subjective well-being in individuals with functional dyspepsia - a path analysis of sex and psychological factors.Frontiers in medicine · 2026Article
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4 authors.
Funding
Abstract
backgroundSubjective well-being (SWB) encompasses both subjective happiness and objective factors. Anxiety and depression are increasingly recognized as contributing causes of functional dyspepsia (FD), yet the role of SWB in FD patients has been largely overlooked. This study aims to investigate the influence of SWB on anxiety, depression, symptom severity, and quality of life (QoL) in individuals with FD.
methodsA total of 374 patients with FD were selected according to Roman IV criteria. Satisfaction with life scale and affect balance scale, Generalized anxiety disorders-7, Patient healthy questionnaire-9, Dyspepsia symptoms severity(DSS)and Nepean dyspepsia index (NDI) were used to assess SWB, anxiety, depression, symptoms severity and QoL, respectively. The results were analyzed using one-way analysis, t-test, Pearson's correlation, and multiple linear regression.
resultsLife satisfaction and emotional balance of FD patients were negatively correlated with DSS, anxiety, depression, and NDI for QoL(r=-0.148,-0.330,-0.325,-0.195, all p < 0.01), (r=-0.205,-0.545, -0.550, -0.357, all p < 0.001), respectively. Multiple linear regression showed that life satisfaction and emotional balance were influencing factors of anxiety (β= -0. 143, p = 0.001), (β= -0. 318, P < 0.001), and depression (β=-0. 122, p = 0.003), (β= -0. 287, p < 0.001), respectively. After removing anxiety and depression, life satisfaction and emotional balance were influencing factors of patients' DSS (β= -0.105, p = 0.049), (β= -0.180, p = 0.001), and QoL (β= -0.117, p = 0.023), (β= -0.329, p < 0.001), respectively.
conclusionsThe SWB of FD patients is negatively associated with disease severity, anxiety, and depression, and positively associated with their quality of life. These results suggested that further strengthening SWB might help reduce symptom severity and improve the QoL of patients, which needs to be confirmed by future follow-up studies.
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