Evidence map›Paper›PMID 40597444›Full record

ArticleMagnetic resonance in medicine2025

Feasibility of strong diffusion encoding and fast readout using a plug-and-play head gradient insert at 7 T.

G C Arends, E Versteeg, A De Luca, F Marc, T H M Roos, D W J Klomp, M Froeling, J C W Siero, C M W Tax

Abstract read
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Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

G C ArendsCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0009-0002-5644-3532
E VersteegCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-3235-3970
A De LucaCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-2553-7299
F MarcCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
T H M RoosCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-3465-7794
D W J KlompCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
M FroelingCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-3841-0497
J C W SieroCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-5079-2868
C M W TaxCenter for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.

Funding

Eurostars FEMSCANHealth Holland Scan2GoUniversitair Medisch Centrum Utrecht Brain Center Young Talent Fellowship 2019Vidi 21299Wellcome TrustWellcome Trust 215944
6 · The paper itself

Abstract

purposeDiffusion weighting is achieved by the application of external field gradients typically for tens of milliseconds, during which the signal also substantially decays due to inherent T

methodsA lightweight (45 kg) single-axis gradient coil operating in the z-direction was interfaced with a 7 T system and operated as an additional fourth-gradient axis to the whole-body gradient setup. Several diffusion MRI experiments were conducted to compare acquisitions taken with a gradient insert operating at full capacity (200 mT/m and 1300 T/m/s) to those using conventional gradient strengths (40-80 mT/m and 200 T/m/s).

resultsA shorter TE of (28.8, 32.4, 38.5, 48.7) ms was achieved using the insert gradient at full capability for readout and diffusion encoding, compared to (49.7, 54.5, 65.9, 85.5) ms (80 mT/m) or (59.9, 68.8, 88.3, 120.9) ms (40 mT/m) for b = (0, 500, 1000, 3000, 10 000) s/mm

conclusionThe results illustrate a successful proof-of-concept for performing diffusion MRI using a plug-and-play head gradient insert at 7 T. Use of low-cost gradient inserts could make advanced diffusion MRI experiments more widely available.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedAlgorithmsBrainEquipment DesignFeasibility StudiesHeadHumansPhantoms, ImagingSignal-To-Noise Ratiodiffusion MRIgradient head inserthigh fieldstrong gradients

Identifiers

PMID40597444
PMCPMC12393193

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.