Evidence map›Paper›PMID 40597326›Full record

ArticleBMC medicine2025

Cumulative health burden and adjustment challenges following road traffic injuries: a controlled prospective study.

Ilaria Pozzato, Yvonne Tran, Mohit Arora, Candice McBain, James W Middleton, Ian D Cameron, Ashley Craig

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ilaria PozzatoKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia. ilaria.pozzato@sydney.edu.au.
Yvonne TranKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Mohit AroraKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Candice McBainKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
James W MiddletonKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Ian D CameronKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Ashley CraigKolling Institute, Faculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.

Funding

State Insurance Regulatory Authority 14/1433
6 · The paper itself

Abstract

backgroundTo investigate the cumulative health burden and complex challenges to adjustment following road traffic injuries (RTIs), this study examined multiple environmental, personal, and health-related factors and outcomes over 12 months in a comprehensive and holistic way, comparing these outcomes between injured and non-injured controls.

methodsA longitudinal controlled cohort study was conducted with two groups: adults with mild to moderate RTIs and non-injured controls. Assessments occurred at 1, 3, 6, and 12 months post-injury. The study involved 120 RTI participants and 112 controls. Data on physiological, psychological, cognitive, and social factors were collected and analyzed using the World Health Organization International Classification of Functioning, Disability, and Health (ICF) framework. The ICF Components-Impairments in Body Functions and Structures, Limitations in Activity, Restrictions to Participation, Environmental and Personal Contextual Factors-were used to link and categorize data and compare outcomes, allowing comprehensive evaluation of RTI-related burden and adjustment challenges.

resultsThe RTI group exhibited significantly worse outcomes across all measured ICF Components, including higher pain, fatigue, psychological distress, and cognitive impairment. Despite some improvements over time, the RTI group continued to experience elevated symptoms, functional limitations, and restricted participation compared to controls at 12 months.

conclusionsRTIs lead to sustained, multidimensional challenges to adjustment, emphasizing the need for early, comprehensive, and ongoing interventions for at least 1-year post-injury. These findings highlight the importance of evaluating multiple biopsychosocial factors and adopting a holistic framework to fully understand recovery patterns. Addressing these factors simultaneously across multiple systems is essential to improve recovery outcomes.

trial registrationACTRN12616001445460.

Indexed as

Accidents, TrafficCost of IllnessWounds and InjuriesAdultFemaleHumansLongitudinal StudiesMaleMiddle AgedProspective StudiesYoung AdultAdjustmentBiopsychosocialBurdenInjuryRoad traffic crashRoad traffic injuries

Identifiers

PMID40597326
PMCPMC12219239

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.