Evidence map›Paper›PMID 40597277›Full record

ArticleArthroplasty (London, England)2025

Restricted kinematic total knee arthroplasty provided better functional outcomes and higher satisfaction rates for Asians of genu varum with apex distal joint line over unrestricted kinematic total knee arthroplasty.

Jia Yi Loh, Ming Han Lincoln Liow, Glen Purnomo, Merrill Lee, Jerry Yongqiang Chen, Hee-Nee Pang, Keng Jin Darren Tay, Seng-Jin Yeo

Abstract read
In one paragraph

Article in Arthroplasty (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jia Yi LohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Ming Han Lincoln LiowDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore. Lincoln.liow.m.h@singhealth.com.sg.ORCID http://orcid.org/0000-0002-4496-8035
Glen PurnomoSt Vincentius a Paulo Catholic Hospital, Surabaya, 60241, Indonesia.
Merrill LeeDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Jerry Yongqiang ChenDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Hee-Nee PangDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Keng Jin Darren TayDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.
Seng-Jin YeoDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, 169608, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCoronal Plane Alignment of the Knee (CPAK) phenotypes I, II, and IV can achieve favorable soft tissue balance following kinematic total knee arthroplasty (KA-TKA). Given that this classification was developed from a Caucasian population, limited studies have evaluated clinical outcomes following restricted vs unrestricted KA-TKA in South-East Asian patients, this study aimed to: (1) outline the prevalence of CPAK types in a South-East Asian population, (2) compare clinical outcomes of patients undergoing restricted versus unrestricted KA-TKA.

methodsProspectively collected data from 232 patients who underwent KA-TKA between 2015 and 2018 were reviewed. The prevalence of CPAK in our cohort was determined using preoperative medial proximal tibial (MPTA) and lateral distal femoral (LDFA) angles measured from long-limb radiographs. Unrestricted calipered KA-TKA targeted equal bone cuts while restricted KA-TKA utilized intraoperative navigation to restrict tibia varus to 4°. Patients were assessed preoperatively, at 6 months, and 2 years using the Knee Society Score, Oxford Knee Score, and Short-Form 36. Postoperative satisfaction and expectation fulfillment were recorded. Intra- and interclass correlation of all radiographic measurements and both parametric and non-parametric statistical analysis were used.

resultsThe prevalence of CPAK in our cohort: I (47.8%), II (30.6%), III (9.1%), IV (7.8%), V (3.9%), VI (0.9%), VII (0%), VIII (0%) and IX (0%). Intra- and interclass correlation of radiographic measurements were excellent at 0.98 (95%CI: 0.95-0.99, P < 0.01). Subgroup analysis of CPAK I patients demonstrated that restricted KA-TKA had better KSS objective (P = 0.04), a higher proportion of satisfied patients (P = 0.02) at 6 months, and better OKS (P = 0.03) than unrestricted KA-TKA.

conclusionCPAK I was the most prevalent phenotype in an Asian population. CPAK I patients undergoing restricted KA-TKA had better functional outcomes and satisfaction rates than those who underwent unrestricted KA-TKA. Future studies should focus on evaluating outcomes of different alignment strategies to personalize treatment for Asian CPAK phenotypes.

Indexed as

ArthroplastyCoronal plane alignment of the kneeCPAKKnee

Identifiers

PMID40597277
PMCPMC12220281

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.