ArticleBMC nursing2025
Effect of bundling auricular acupressure and fluid restriction program on salivary flow rate and fluid control adherence among children undergoing hemodialysis: a randomized control trial.
Article in BMC nursing, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06562959 (Effect of Integrating Auricular Acupressure and Fluid Restriction Program on Salivary Flow Rate and Fluid Control Adherence Among Children Undergoing Haemodialysis), which is not on this map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effect of Integrating Auricular Acupressure and Fluid Restriction Program on Salivary Flow Rate and Fluid Control Adherence Among Children Undergoing Haemodialysis
Who cites it
1 citing paper in PubMed.
- The effectiveness of individualized thirst management in patients with postoperative thirst for gastric cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
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4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe adverse effect of chronic kidney disease extends far beyond the primary impact on kidney function. Children undergoing Haemodialysis (HD) develop several oral complications such as decreased salivary flow rate and xerostomia. This creates a vicious cycle where the compulsive urge to drink further contributes to fluid overload. Providing a standalone program may not be sufficient to ensure full adherence to fluid restrictions. Auricular Acupressure (AA) induces parasympathetic stimulation which increases salivary flow rate and alleviate persistent feeling of thirst.
aimto assess the effect of bundling AA and fluid restriction program on salivary flow rate and fluid control adherence among children undergoing HD.
methodsA single-blinded randomized control trial was conducted at Alexandria University Children's Hospital in Smouha, Egypt. A sample of 60 children receiving HD was randomly assigned to two parallel groups. The control group received the fluid restriction program through general small-group discussion sessions, individualized consultations, and follow-up. The study group also received the intervention bundle: the fluid restriction program and twelve sessions of AA on four acupoints: Shenmen, Kidney Concha, Point Zero, and Upper Tragus.
resultsSubjective assessment revealed significant differences in all the parameters of salivary flow rate, such as difficulty in swallowing (p = 0.005), saliva rate in mouth (p = 0.016), dryness in mouth (0.009), dryness in lips (p = 0.002). The objective assessment of the salivary flow rate unveiled that applying the intervention bundle resulted in a notable increase in salivation level (from 33.3 to 86.7%) with p-value > 0.001 compared to a slight increase in the control group (23.3-36.7%). There was a significant improvement in the overall fluid control adherence in both groups with favor to the study group who received the intervention bundle as p-values were < 0.001and 0.047 respectively.
conclusionBundling AA and fluid restriction programs effectively improved salivary flow rate and fluid control adherence among children undergoing HD attending the HD unit in Alexandria University Children's Hospital at Smouha, Egypt. Therefore, nurses working in HD units may adopt this intervention bundle as a cost-effective, safe, and complementary tool to promote sustainable patient adherence to fluid-restriction regimen. TRIAL REGISTRATION NUMBER: [NCT06562959], ClinicalTrails.gov, Retrospectively registered (April 8th, 2024), URL of trial registry record: https://clinicaltrials.gov/study/NCT06562959 .
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