Evidence map›Paper›PMID 40597221›Full record

ArticleBMC medicine2025

Causal link between humid heatwaves and ischemic heart disease: assessing hospitalizations and economic burden across 955 Chinese counties.

Teng Wang, Hanxu Shi, Zhisheng Liang, Haojun Fan, Taojiang Meng, Fan Dai, Wei Huang, Ming Xu, Huining Yang, Shyam Biswal and 5 more

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Teng Wang *School of Public Health, Peking University, Beijing, China.
Hanxu Shi *School of Public Health, Peking University, Beijing, China.
Zhisheng LiangSchool of Public Health, Peking University, Beijing, China.
Haojun FanInstitute of Disaster and Emergency Medicine, Tianjin University, Tianjin, China.
Taojiang MengEmergency General Hospital, Beijing, China.
Fan DaiSchool of Law, California-China Climate Institute, UC Berkeley, Berkeley, CA, USA.
Wei HuangInstitute of Environmental and Health, Peking University School of Public Health, Beijing, China.
Ming XuSchool of Public Health, Peking University, Beijing, China.
Huining YangDepartment of Disease Prevention and Control, Third Medical Center, General Hospital of the People's Liberation Army, Beijing, China.
Shyam BiswalBloomberg School of Public Health, Johns Hopkins University, Baltimore, USA.
Murugappan RamanathanSchool of Medicine, Johns Hopkins University, Baltimore, USA.
Gorden G LiuInstitute for Global Health and Development, Peking University School of Public Health, Beijing, China.
Minghui RenSchool of Public Health, Peking University, Beijing, China.
Shengzhi SunSchool of Public Health, Capital Medical University, Beijing, China.
Zhenyu ZhangSchool of Public Health, Peking University, Beijing, China. zzy@pku.edu.cn.

Funding

Bill & Melinda Gates INV-062194
6 · The paper itself

Abstract

backgroundHumid heatwaves might cause more massive destruction to human health systems, especially the cardiovascular system. However, there is no systematic approach for identifying humid heatwaves and assessing their impacts on human health and health-related economic burden. This study aims to elucidate the relationship between short-term exposure to humid heatwaves and the relative risk of hospitalization for ischemic heart disease (IHD) and the hospitalization-related economic burdens.

methodsThis study utilizes hospitalization data from the Chinese Multiple-County (CMC) Hospital Network with 6,843,511 IHD cases across 1309 counties from 2016 to 2022. We employed a pre-post analysis and a causal inferential propensity score matching aided difference-in-differences (PSM-DID) approach to assess the causal effect of each type of humid heatwaves on IHD hospitalization rate changes.

resultsIHD hospitalizations increased by 2.92% (95% CI, 1.17%, 4.66%), 2.76% (95% CI, 1.07%, 4.45%), and 1.60% (95% CI, 0.08%, 3.12%) following independent humid heatwaves, light precipitation involved-, and moderate precipitation involved-humid heatwaves, with annual hospitalization-related economic burden reached $154 million (95% CI, $20, $249 million), $75 million (95% CI, $14, $136 million), and $81 million (95% CI, $31, $131 million), respectively. Chronic IHD and Angina were the most sensitive subtypes. Moreover, middle-to-old and male populations were afforded the most burdens.

conclusionsAs humid heatwaves become more intense, older populations with IHD should be provided with more care and medical resources. Identifying strategies and implementing actionable adaptation measures to minimize disruptions in healthcare delivery following these extremely hot and humid events is crucial to reducing IHD hospitalizations.

Indexed as

Cost of IllnessExtreme HeatHospitalizationHot TemperatureHumidityMyocardial IschemiaAdultAgedChinaEast Asian PeopleFemaleHumansMaleMiddle AgedEconomic burdenHumid heatwaveIschemic heart diseasePrecipitationPropensity score matching aided difference-in-differences (PSM-DID)

Identifiers

PMID40597221
PMCPMC12211259

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.