ArticleBMC psychiatry2025
Association of insomnia with suicide attempts in Chinese chronic schizophrenia patients with and without autistic symptoms.
Article in BMC psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Arginine-vasopressin systems in autistic phenotype schizophrenia: effect of a genetic variant of AVPR1a and AVPR1b.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Associations of inflammatory biomarkers with brain atrophy and clinical scores in schizophrenia patients with autistic features.BMC research notes · 2026Article
- Sleep in Early Psychosis and Bipolar Disorder: Preliminary Results on Actigraphic and Self-Reported Markers of Vulnerability.Early intervention in psychiatry · 2026Article
- Association Between Specific Insomnia Symptoms and Aggression in Chinese Patients with Chronic Schizophrenia: A Large-Scale Cross-Sectional Study.Nature and science of sleep · 2025Article
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Authors and funding
8 authors.
Funding
Abstract
backgroundNumerous studies have shown that people with schizophrenia (SCZ) have a higher risk of suicide, and insomnia symptoms are common in SCZ patients. Autism symptoms (AS) are common in SCZ patients, and they are strongly linked to suicide. This study explored the connection between insomnia, autistic symptoms, and suicide attempts in Chinese patients with SCZ, it has not yet been investigated.
methods955 Chinese chronic SCZ patients provided demographic and clinical information for data collection. Insomnia Symptom Severity Index (ISI) was used to assess the severity of insomnia symptoms, and Beck Scale for Suicide Ideation (BSS) was used to assess the risk of suicide. PANSS Autism Severity Score (PAUSS) was used to assess autistic symptoms.
resultsThe incidence of insomnia was higher in AS-SCZ patients than in non-AS-SCZ patients, but the incidence of suicide attempts was lower than that in non-AS-SCZ patients (all p < 0.05). In SCZ patients, insomnia severity scores were strongly associated with suicide attempts. Further correlational analysis showed that this association was only present in non-AS-SCZ patients (p < 0.05).
conclusionsInsomnia in patients with chronic SCZ may be influenced by autistic symptoms, potentially impacting the association between suicide attempts and insomnia.
trial registrationThe study was a cross-sectional study, so there was no clinical trial registration. CLINICAL TRIAL NUMBER: not applicable.
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