Evidence map›Paper›PMID 40597151›Full record

ArticleBMC oral health2025

Two oral verrucous carcinomas in a patient with oral graft vs. host disease- recurrent verrucous carcinoma: a case report.

Jiaqi Huang, Qiaozhi Jiang, Jiaxuan Liu, Guocheng Mei, Renchuan Tao

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiaqi Huang *Department of Periodontics and Oral Medicine, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China.
Qiaozhi Jiang *Department of Periodontics and Oral Medicine, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China.
Jiaxuan LiuDepartment of Periodontics and Oral Medicine, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China.
Guocheng MeiDepartment of Periodontics and Oral Medicine, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China.
Renchuan TaoDepartment of Periodontics and Oral Medicine, College of Stomatology, Guangxi Medical University, Nanning, Guangxi, China. taorenchuan@gxmu.edu.cn.

Funding

National Natural Science Foundation of China 82370959Youth Science Foundation Project of Guangxi Medical University Natural Science Foundation GXMUYSF202431Youth Science Foundation Project of Guangxi Natural Science Foundation 2024GXNSFBA010284
6 · The paper itself

Abstract

Patients who undergo allogeneic hematopoietic stem cell transplantation (allo-HSCT) frequently experience immunodeficiency, predisposing them to graft-versus-host disease (GVHD) and viral infection. The oral cavity is a common organ affected by chronic GVHD(cGVHD), which can lead to the development of secondary malignant tumors such as oral squamous cell carcinoma (OSCC). Verrucous carcinoma is a low-grade variant of SCC with specific morphologic, cytokinetic and clinical features. It is a locally aggressive tumour and does not metastasize to regional lymph nodes or to distant sites. This case report describes a patient with cGVHD following allo-HSCT who developed extensive oral verrucous carcinoma in the oral mucosa. This observation underscores the importance of regular oral examinations for transplant recipients, particularly those with cGVHD, to monitor HPV infection and the potential development of verrucous carcinoma.

Indexed as

Carcinoma, VerrucousGraft vs Host DiseaseHematopoietic Stem Cell TransplantationMouth NeoplasmsNeoplasm Recurrence, LocalHumansMaleMiddle AgedCase reportGraft-versus-host DiseaseHematopoietic stem cell transplantatioOral verrucous hyperplasia

Identifiers

PMID40597151
PMCPMC12217826

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.