Trial reportBMC oral health2025
Effect of single-dose diode laser photobiomodulation on orthodontic pain following initial archwire placement: a randomized clinical trial.
Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07456709 (Efficacy of Different Regiments of 980 nm Low-Level Laser Therapy to Reduce Pain Caused by Orthodontic Separators), which is not on this map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Efficacy of Different Regiments of 980 nm Low-Level Laser Therapy to Reduce Pain Caused by Orthodontic Separators: A Randomized, Double-Blind, Split-Mouth Placebo-Controlled Study
Who cites it
3 citing papers in PubMed.
- Laser-Based Photobiomodulation for Orthodontic Pain: Mechanistic Evidence from Experimental Tooth-Movement Models.International journal of molecular sciences · 2026Review
- Efficacy of Different Regimens of 980 nm Low-Level Laser Therapy to Reduce Pain Caused by Elastomeric Separator Placement in Adults: A Randomized, Double-Blind, Split-Mouth Placebo-Controlled Study.Journal of clinical medicine · 2026Article
- A scientometric study on research trends and characteristics of randomized controlled trials in orthodontics.Journal of dental sciences · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study assessed the effect of photobiomodulation (PBM) through single-dose diode 940 nm laser on pain after initial archwire placement.
methodsThis parallel-design clinical trial with 1:1 allocation ratio was conducted on 120 orthodontic patients with Class I molar relationship and 3-6 mm crowding, or overbite. Orthodontic brackets had been previously placed by an orthodontist. The patients were randomly assigned to three groups (n = 40) of PBM, placebo (laser in off mode), and control (no intervention). Right after initial archwire placement, patients in PBM group underwent 940 nm laser irradiation with 32 J/cm
resultsType of intervention had no significant effect on VAS pain score (P = 0.654) although slightly lower pain was recorded in the PBM group. Location of orthodontic wire placement (maxilla/mandible) had no significant effect on the pain score (P = 0.780), although the mean pain score in the mandible was slightly higher than that in the maxilla.
conclusionIn the present study, PBM delivered using a single-session 940 nm diode laser had no significant effect on pain after initial placement of orthodontic archwires.
trial registrationTrial registration number: IRCT20230603058377N1. Retrospectively registered. Registration date: 08/07/2023.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.