Evidence map›Paper›PMID 40597117›Full record

ArticleBMC medicine2025

Prevalence and progress of underdiagnosis of probable dementia: a repeated cross-sectional study in 19 European countries.

Jiazhou Yu, Pengyun Wang, Shangkun Xie, Jay Amin, Christoph Mueller, Xiaohui Hou, Xi Chen, Benjamin R Underwood, Shangfeng Tang, Shanquan Chen

Abstract read
In one paragraph

Article in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Inequities in Dementia Diagnosis: Evidence From the ELSI-Brazil Study.International journal of geriatric psychiatry · 2026
    Article
  6. Article
  7. Article
  8. Real-world prediction of early-onset dementia by health record data: A multi-center machine learning study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiazhou YuDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China.
Pengyun WangUniversity of Oxford, Oxford, UK.
Shangkun XieSchool of Economics, Nankai University, Tianjin, China.
Jay AminClinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Christoph MuellerKing's College London, London, UK.
Xiaohui HouThe World Bank, Washington, DC, 20433, USA.
Xi ChenSchool of Public Health, Yale University, New Haven, CT, USA.
Benjamin R UnderwoodDepartment of Psychiatry, University of Cambridge, Cambridge, UK.
Shangfeng TangSchool of Medicine and Health Management, Tongji Medical College of Huazhong University of Science and Technology, Qiaokou District, No.13, Hangkong Road, Wuhan, 430030, Hubei, China. sftang2018@hust.edu.cn.
Shanquan ChenSchool of Public Health, LKS Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China. shanquan.chen@lshtm.ac.uk.

Funding

A Life Course Approach to Understanding Racial and Ethnic Disparities in Alzheimer's Disease and Related Dementias and Health CareR01AG077529 · NIA · YALE UNIVERSITY · PI Xi Chen · 2022 to 2026
$3.6M
National Key R&D Program of China 2023YFC3606400NIA NIH HHS R01 AG077529
6 · The paper itself

Abstract

backgroundUnderdiagnosis of dementia remains a significant public health challenge in Europe, with nearly half of those meeting clinical criteria not receiving a formal diagnosis. Recent healthcare initiatives have aimed to improve diagnostic processes, but the extent of progress varies across countries.

methodsWe analyzed data of 10,402 participants from the Survey of Health, Ageing, and Retirement in Europe (SHARE) across 19 countries from 2011-2015 to 2015-2019. Underdiagnosis of probable dementia was defined as probable dementia (based on cognition score) without a confirmed diagnosis. Weighted logistic regression was conducted to examine temporal trends in underdiagnosis of probable dementia and to identify individual- and country-level predictors of progress in diagnosis.

resultsA significant reduction in underdiagnosis of dementia was observed between the two periods, consistent across most countries. Progress in diagnosis was modified by country-level factors such as number of psychiatrists, formal long-term care worker at home or institutions, and positron emission tomography and individual-level factors including age, education, retirement status, nursing home residency, multimorbidity, and healthcare utilization patterns.

conclusionsThe decreasing trend in underdiagnosis highlights the importance of targeted interventions including investment in psychiatric care services. Understanding remaining disparities is crucial for informing health policies and addressing inequalities to dementia diagnosis and care.

Indexed as

DementiaAgedAged, 80 and overCross-Sectional StudiesEuropeFemaleHumansMaleMiddle AgedPrevalenceDementiaDiagnosisDisparityEuropeanUndiagnosed

Identifiers

PMID40597117
PMCPMC12219912

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.