ArticleBMC medical informatics and decision making2025
The impact of a patient decision aid for patients with advanced laryngeal carcinoma - a multicenter study.
Article in BMC medical informatics and decision making, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03292341 (Evaluating a Decision Aid in Clinical Practice for Patients With T3/T4 Laryngeal Cancer), which is not on this map. Not yet cited in PubMed.
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Evaluating a Decision Aid in Clinical Practice for Patients With T3/T4 Laryngeal Cancer
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12 authors.
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Abstract
purposePatients with advanced larynx cancer face challenging treatment decisions. To address this, we developed and tested a patient decision aid (PDA), aiming to reduce decisional conflict (DC), and enhance knowledge and perceived shared decision-making (SDM).
methodsIn this multicenter study (ClinicalTrials.gov ID: NCT03292341, 2016-2023), a pre/post study design was used. Participants, meeting the inclusion criteria of advanced larynx cancer without distant metastasis, completed questionnaires on knowledge, DC and SDM immediately after counseling (T1) and 6 months post-treatment (T2). The intervention arm utilized the PDA (see https://beslissamen.nl/pda_launch.html?pda=tools/pda_larynx_en/story.html ) before completing T1 questionnaires, while the usual care arm followed standard procedures. Between-group differences in outcomes were estimated using regression models with correction for case mix differences.
resultsTotal DC score was significantly lower in the intervention arm (n = 46) compared to the usual care arm (n = 45) (adjusted mean difference - 32, 95% CI: -37.4; -26.1, p < 0.001). The intervention group demonstrated significantly higher overall knowledge (mean 69% correct) than the control group (mean 47% correct)(adjusted mean difference 24, 95% CI 15.3; 33.1, p < 0.001). Almost all patients in usual care (44/45, 98%) experienced clinically significant DC (CSDC, DCS > 25), compared to 89% (41/46) in the intervention arm (adjusted OR 0.25, 95%CI 0.01; 1.9) p = 0.238). Perceived SDM was significant higher in the intervention arm (mean 78.16) compared to the usual care arm (mean 70.32); however, both groups exhibited high levels.
conclusionThe PDA for advanced laryngeal cancer effectively reduced decisional conflict, enhanced patients' knowledge and improved perceived SDM.
trial registrationClinicalTrials.gov ID NCT03292341, 20,151,231. LEVEL OF EVIDENCE: 3:
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