Evidence map›Paper›PMID 40597039›Full record

Observational studyBMC ophthalmology2025

Prevalence and clinical characteristics of ocular sarcoidosis among non-infectious uveitis in a Chinese tertiary ophthalmic center: a retrospective observational study.

Daquan He, Tianyu Tao, Xuening Peng, Jianjie Lv, Wenru Su

Abstract readObservational Study
In one paragraph

Observational study in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. [Clinical features and prognosis of sarcoidosis with ocular lesions as the initial manifestation].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daquan He *State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Tianyu Tao *Department of Ophthalmology, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Xuening PengState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Jianjie LvState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Sun Yat-sen University, Guangzhou, China.
Wenru SuDepartment of Ophthalmology, Shanghai Key Laboratory of Orbital Diseases and Ocular Oncology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine, No. 58, Puyu E. Rd, Huangpu Dist, Shanghai, 200011, China. suwenru@sjtu.edu.cn.ORCID https://orcid.org/0000-0002-0506-6362

Funding

National Outstanding Youth Science Fund Project of China 82122016
6 · The paper itself

Abstract

backgroundThe prevalence of ocular sarcoidosis (OS) varies across Asia and the application of the most recent revised diagnostic criteria has not yet been fully adopted. Thus, the prevalence of OS within the Chinese population remains uncertain. We investigate the prevalence of OS among non-infectious uveitis in China, with the Revised criteria of International Workshop on OS.

methodsIn this study, we retrospectively reviewed the medical records of 406 patients who had undergone routine computed tomography scans between May 2019 and June 2023. The diagnosis of OS was made according to the Revised criteria of International Workshop on Ocular Sarcoidosis (IWOS). We further reviewed the clinical characteristics of four patients, including age, gender, anatomical type of uveitis, ocular manifestations, ocular examinations, visual acuity, and complications.

resultsOut of 254 patients with noninfectious uveitis who completed computed tomography, 138 (54.3%) were men, and 116 (45.6%) were women, with a mean age of 38.9 years (ranging from 6 to 77 years). Among the 254 patients with non-infectious uveitis, OS accounted for 1.57% of the cases, however, Behcet's disease (14.5%) was the predominant etiology, followed by Vogt-Koyanagi-Harada disease (12.9%), retinal vasculitis (1.1%), multifocal choroiditis (1.1%), sympathetic ophthalmia (1.1%), punctate inner choroidopathy (0.7%), and acute posterior multifocal placoid pigment epitheliopathy (0.3%). The study revealed that 3 patients were diagnosed with definite OS, and 1 had presumed OS. Among 406 patients who underwent computed tomography, 0.98% (4/406) of patients met the Revised criteria of IWOS, 1.37% (4/290) of patients with uveitis, and 1.57% (4/254) of patients among non-infectious uveitis.

conclusionsThis study determined the prevalence of OS among non-infectious uveitis in China, and described the clinical characteristics of four individuals.

Indexed as

SarcoidosisUveitisAdolescentAdultAgedChildChinaEast Asian PeopleFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesTertiary Care CentersTomography, X-Ray ComputedChinaComputed tomographyNon-infectious uveitisOcular sarcoidosisPrevalence

Identifiers

PMID40597039
PMCPMC12220122

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.