Evidence map›Paper›PMID 40596999›Full record

ArticleBMC pediatrics2025

Spontaneous renal artery thrombosis causing circulatory insufficiency in a newborn- a case report.

Sjors P Marijnen, Bart Straver, Iona Madden, Jelena Stojanovic, Cornelis R van der Torren, Marita de Waard, Bram B M van der Meijs, Rik Westland

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In one paragraph

Article in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Sjors P MarijnenDepartment of Pediatrics, Emma Children's Hospital- Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Bart StraverDepartment of Pediatric Cardiology, Emma Children's Hospital- Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Iona MaddenDepartment of Pediatric Nephrology, Great Ormond Street Hospital for Children, London, UK.
Jelena StojanovicDepartment of Pediatric Nephrology, Great Ormond Street Hospital for Children, London, UK.
Cornelis R van der TorrenDepartment of Pediatric Hematology, Emma Children's Hospital- Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Marita de WaardDepartment of Neonatology, Emma Children's Hospital- Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Bram B M van der MeijsDepartment of Radiology and Nuclear Medicine, Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
Rik WestlandDepartment of Pediatric Nephrology, Emma Children's Hospital- Amsterdam UMC, location University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands. ri.westland@amsterdamumc.nl.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRenal artery thrombosis in newborns is a severe condition with high morbidity and mortality. Although neonates harbor intrinsic and external risk factors for thrombotic events of the renal vasculature, their occurrence is rare and requires swift diagnosis and treatment in a multidisciplinary setting. CASE PRESENTATION: We report a case of a 3-day old newborn, with a normal pregnancy and birth, who presented with gross hematuria, fever, and cardiac decompensation due to left renal artery thrombosis. In addition to moderate dehydration, we could not identify any clinical risk factors for renal artery thrombosis adding to this unique presentation. Rapid but controlled blood pressure treatment and percutaneous angioplasty of the left renal artery to restore patency were successful in normalizing the cardiac function and circulatory condition. However, atrophy of the left kidney was identified during follow-up, implicating life-long consequences on the health of this patient.

conclusionNeonatal renal artery thrombosis may present as gross hematuria and hypertension in newborns, even in the absence of umbilical catheterization or thromboembolic disorders, and requires swift, multidisciplinary treatment to prevent morbidity and mortality.

Indexed as

Renal ArteryRenal Artery ObstructionThrombosisHematuriaHumansInfant, NewbornCase reportGross hematuriaNeonatal hypertensionNeonatal percutaneous transluminal angioplastyRenovascular thrombosis

Identifiers

PMID40596999
PMCPMC12217276

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