Evidence map›Paper›PMID 40596981›Full record

ArticleBMC ophthalmology2025

Micro-interventional pre-treatment for nucleus disassembly in the setting of non-cavitating sonic lensectomy: real-world evidence study in 512 cases.

Sean Ianchulev, Elizabeth Yeu, Edward H Hu, Gautam Kamthan, Seth Pantanelli, Paul Singh, Farrell Tyson

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sean IanchulevOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA.
Elizabeth YeuRefractive Surgery, Virginia Eye Consultants, Norfolk, VA, USA.
Edward H HuWolfe Eye Clinic, Marshalltown, IA, USA.
Gautam KamthanOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, New York, NY, USA. gautamkamthanmd@gmail.com.
Seth PantanelliDepartment of Ophthalmology, Penn State College of Medicine, Hershey, PA, USA.
Paul SinghThe Eye Centers of Racine and Kenosha, Racine, WI, USA.
Farrell TysonThe Cape Coral Eye Center (Tyson), Cape Coral, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the effect of adjunct micro-interventional pre-treatment for nucleus disassembly on the surgical efficiency of non-cavitating lensectomy during cataract surgery. METHODS AND ANALYSIS: 12 surgeons performed 512 consecutive cataract extractions using a sonic cavitation-free lensectomy with or without adjunct pre-treatment for nucleus disassembly. There were 2 interventional arms including (1) lensectomy without adjunct pre-treatment and (2) lensectomy with micro-interventional miLOOP pre-treatment.

resultsSuccessful lensectomy was achieved in all eyes using cavitation-free sonic lensectomy. Average baseline cataract density was 2.28 and 2.39 in the three groups, respectively. Compared to no pre-treatment, nucleus evacuation time was 24% (p = < 0.001) faster with micro-interventional nucleus disassembly. Irrigation/aspiration (I/A) time was 14% faster with the micro-interventional pre-treatment (p = < 0.001). Irrigation fluid use was 24% less with micro-interventional. There was a low rate of capsular tear of 1 case across 512 cases with no other unanticipated complications.

conclusionMicro-interventional pre-treatment for nucleus disassembly was associated with improved lensectomy time and fluidic efficiency compared to no pre-treatment. Non-cavitating lensectomy with the miCOR lens pen achieved effective fragmentation and extraction in all grades of cataract.

Indexed as

Cataract ExtractionLens Nucleus, CrystallineMicrosurgeryPhacoemulsificationAgedAged, 80 and overCataractFemaleHumansMaleMiddle AgedRetrospective StudiesVisual AcuityCataract surgeryFemtosecondmiCORmiLOOP

Identifiers

PMID40596981
PMCPMC12220116

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.