Evidence map›Paper›PMID 40596934›Full record

SynthesisBMC gastroenterology2025

Comparison of efficacy and safety between surgical and conservative treatments for hemorrhoids: a meta-analysis.

Longfang Quan, Xuelian Bai, Fang Cheng, Jin Chen, Hangkun Ma, Pengfei Wang, Ling Yao, Shaosheng Bei, Xiaoqiang Jia

Abstract readMeta-AnalysisComparative StudySystematic Review
In one paragraph

Synthesis in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Longfang Quan *Department of Anorectal, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, No. 1 Road Xi Yuan Cao Chang, Haidian District, Beijing, 100091, China.
Xuelian Bai *Department of Management, Xiyuan Hospital of China Academy of Traditional Chinese Medicine 100091, Beijing, China.
Fang ChengDepartment of Anorectal, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, No. 1 Road Xi Yuan Cao Chang, Haidian District, Beijing, 100091, China.
Jin ChenDepartment of Management, Xiyuan Hospital of China Academy of Traditional Chinese Medicine 100091, Beijing, China.
Hangkun MaDepartment of Emergency, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, Beijing, 100091, China.
Pengfei WangDepartment of Traditional Chinese Medicine, Fuzhou University Affiliated Provincial Hospital, Fuzhou, 350001, China.
Ling YaoDepartment of Anorectal, Guang'anmen Hospital, China Academy of Chinese Medical Sciences, Beijing, 100053, China.
Shaosheng BeiDepartment of Anorectal, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, No. 1 Road Xi Yuan Cao Chang, Haidian District, Beijing, 100091, China. xyyybss@163.com.
Xiaoqiang JiaDepartment of Anorectal, Xiyuan Hospital of China Academy of Traditional Chinese Medicine, No. 1 Road Xi Yuan Cao Chang, Haidian District, Beijing, 100091, China. jxq391@sina.com.

Funding

Xiyuan Hospital of CACMS NO. XYZX0203-03
6 · The paper itself

Abstract

objectivesHemorrhoids, a common anorectal condition, can be managed through surgical or conservative treatments. The aim of this meta-analysis is to compare the efficacy and safety of surgical and conservative treatments for hemorrhoids.

methodsA systematic search was conducted from of PubMed, Embase, the Cochrane Library, and Web of Science from their inception to September 25, 2024. Eligible studies compared surgical treatments with non-invasive conservative treatments in hemorrhoids. Statistical analyses included pooled odds ratios (ORs) and mean differences (MDs)/standard mean differences (SMDs) with 95% confidence intervals (CIs).

resultsSeven studies, including 760 patients, were analyzed. Surgery achieved higher rates of complete symptom resolution than conservative therapy (OR = 2.96, 95% CI: 1.66-5.28, p < 0.001). Overall pain scores favored surgery (SMD = -0.93, 95% CI: 1.73 to -0.13, p = 0.02). Subgroup analysis showed clear superiority within four days (SMD = -1.26, 95% CI -1.84 to -0.68) but parity beyond ten days (SMD = 0.00, 95% CI -0.44 to 0.44; p = 0.99). Comparable patterns were observed in pregnant women with thrombosed external hemorrhoids. Rates of postoperative bleeding (OR: 1.09; 95% CI: 0.42 to 2.82, p = 0.86; I2 = 41%, p = 0.15) and urinary retention (OR: 1.75; 95% CI: 0.30 to 10.31, p = 0.54; I2 = 45%, p = 0.18) did not differ significantly between groups. Surgical-specific adverse events were infrequent (incontinence 3%, persistent pain 5%, watery discharge 6%). Surgery shortened recovery in pregnant thrombosed cases by approximately seven days (MD: -6.80; 95% CI: -7.64 to -5.96, p < 0.001; I2 = 55%, p = 0.14) and reduced overall recurrence (95% CI: 0.10 to 0.37, p < 0.001; I2 = 0%, p = 0.97).

conclusionSurgical treatments provide superior symptom relief, faster recovery, and lower recurrence but with some specific post-treatment complications, while conservative treatments are safer and less invasive but with provides slower symptom relief and higher recurrence rates. Individualized treatment should consider symptom severity, patient preferences, and risk tolerance.

Indexed as

Conservative TreatmentHemorrhoidectomyHemorrhoidsFemaleHumansPregnancyTreatment OutcomeConservative treatmentHemorrhoidsMeta-AnalysisSurgical treatment

Identifiers

PMID40596934
PMCPMC12211330

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.