Evidence map›Paper›PMID 40596931›Full record

ArticleBMC ophthalmology2025

Evaluating ocular torsion following inferior oblique weakening in superior oblique palsy: a pilot study using color fundus photography and spectral domain optical coherence tomography.

Kaveh Abri Aghdam, Afsane Katiraee, Samira Chaibakhsh, Mostafa Soltan Sanjari, Arezoo Miraftabi, Fateme Nadjafi, Ali Sadeghi, Vahid Zare Hosseinabadi, Amin Zand

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Kaveh Abri AghdamEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Afsane KatiraeeEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Samira ChaibakhshEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Mostafa Soltan SanjariEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Arezoo MiraftabiEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Fateme NadjafiEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Ali SadeghiEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Vahid Zare HosseinabadiEye Research Center, Ophthalmology Department, Rassoul Akram Hospital, School of Medicine, The Five Senses Health Institute, Iran University of Medical Sciences, Tehran, Iran.
Amin ZandClinical Research Development Unit, Shafa Hospital, Kerman University of Medical Sciences, Shafa St. 7616913555, Kerman, Iran. sandpost3@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare spectral domain optical coherence tomography (OCT) and color fundus photography (CFP) for assessing ocular cyclotorsion in unilateral congenital superior oblique palsy (SOP) before and after inferior oblique disinsertion.

methodsThis prospective pilot study evaluated 18 patients (36 eyes) with unilateral congenital SOP. Disc-foveal angle (DFA) was measured preoperatively and 3 months postoperatively using CFP (analyzed with ImageJ) and Spectralis OCT (with FoDi software). Contralateral nonparetic eyes served as controls.

resultsPreoperative hypertropia (14.31 ± 4.15 prism diopter, PD) significantly improved postoperatively (1.46 ± 1.98 PD, P < 0.001). CFP measurements showed significantly greater cyclotorsion in paretic versus nonparetic eyes preoperatively (P = 0.001), while OCT revealed no inter-eye difference (P = 0.295). In paretic eyes, CFP-derived DFAs were significantly higher than OCT values both preoperatively (12.26 ± 4.72° vs. 8.87 ± 4.56°, P = 0.002) and postoperatively (7.25 ± 5.18° vs. 4.33 ± 3.98°, P = 0.005). Nonparetic eyes showed no significant inter-method differences at either timepoint (all P > 0.05). Inter-method reliability was moderate preoperatively (ICC = 0.693 paretic, 0.657 nonparetic) and improved postoperatively (ICC = 0.718 and 0.921, respectively). Bland-Altman analysis demonstrated narrowing limits of agreement postoperatively (nonparetic: 8.48° to 4.40°; paretic: 7.97° to 7.50°), with no systematic bias.

conclusionSpectralis OCT with FoDi software provides a clinically useful alternative to CFP for cyclotorsion assessment in congenital SOP, though it may systematically underestimate DFA values in paretic eyes.

Indexed as

Oculomotor MusclesPhotographyTomography, Optical CoherenceTorsion AbnormalityTrochlear Nerve DiseasesAdolescentAdultChildChild, PreschoolFemaleFundus OculiHumansMaleMiddle AgedPilot ProjectsProspective StudiesCongenital superior oblique palsyDisc-foveal angleFoDi softwareFundus photographyInferior oblique weakeningOcular torsionSpectralis OCTVertical strabismus

Identifiers

PMID40596931
PMCPMC12220215

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.