Evidence map›Paper›PMID 40596928›Full record

ArticleBMC infectious diseases2025

Prevalence of common respiratory viruses in children: insights from post-pandemic surveillance.

Constance Adu-Gyamfi, Jesse Addo Asamoah, James Opoku Frimpong, Richard Larbi, Richard Owusu Ansah, Sherihane Naa Ayeley Aryeetey, Richmond Gorman, Henry Kyeremateng Acheampong, Emmanuella Nyarko-Afriyie, Manuella Hayford and 11 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Constance Adu-GyamfiKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Jesse Addo AsamoahKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
James Opoku FrimpongDepartment of Clinical Microbiology, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Richard LarbiGenomics and Infectious Diseases Laboratory, Faculty of Allied Health Sciences (FAHS), Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Richard Owusu AnsahGenomics and Infectious Diseases Laboratory, Faculty of Allied Health Sciences (FAHS), Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Sherihane Naa Ayeley AryeeteyKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Richmond GormanKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Henry Kyeremateng AcheampongKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Emmanuella Nyarko-AfriyieKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Manuella HayfordKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Henrietta Dede TettehKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Kwadwo BoampongDepartment of Theoretical and Applied Biology, College of Science, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Veronica BarnorSchool of Medicine and Dentistry, College of Health Sciences, Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana.
Peter K BrenyaHopeXchange Medical Centre, Kumasi, Ghana.
Frederick AyensuHopeXchange Medical Centre, Kumasi, Ghana.
Nana Kwame Ayisi-BoatengKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Philip El-DuahInstitute of Virology - Charité - Universitӓtsmedzin Berlin, Berlin, Germany.
Christian DrostenInstitute of Virology - Charité - Universitӓtsmedzin Berlin, Berlin, Germany.
Richard Odame PhillipsKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana.
Augustina Angelina SylverkenKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana. asylverken@knust.edu.gh.
Michael OwusuKumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Kumasi, Ghana. michaelowusu80@gmail.com.

Funding

Deutscher Akademischer Austauschdienst 57592595
6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has significantly affected healthcare systems worldwide, impacting the occurrence and management of respiratory illnesses. This has also influenced respiratory infections' role in childhood mortality. Surveillance of common respiratory viruses in Ghana is limited, making it crucial to assess the prevalence of respiratory viral infections, particularly in children, in the post-pandemic era. This study provides data on the prevalence of respiratory viruses and the associated risk factors in symptomatic children aged 5 or younger in an urban paediatric hospital setting.

methodsThe study was a cross-sectional study with a convenience sampling method, conducted in four health facilities: Asokwa Children's Hospital, HopeXchange Medical Centre, University Health Services-KNUST, and Kumasi South Hospital in Kumasi, Ghana, between August 2022 and June 2023. Recruitment was not done in parallel in each hospital. Oropharyngeal swabs were collected from 303 children ≤ 5 years old and screened by RT-qPCR for common respiratory viruses.

resultsOut of the 303 patients enrolled in the study, 165 (54.4%) were male, and 122 (40.3%) were aged from 13 to 36 months. The median age of the patients was 19 months. The most common symptoms reported were cough (87.0%), runny nose (87.0%), and fever (72.0%). Respiratory viruses were detected in 100 (33.0%) of the samples, with 36 (12.0%) testing positive for Human metapneumovirus (HMPV), 27 (8.9%) for Respiratory syncytial virus (RSV), and 20 (6.6%) for Human Adenovirus (HAdV). In 8.0% of the cases, multiple viruses were detected, with HAdV being the most common (75.0%). Children under 6 months (AOR: 4.81, 95% CI: 1.20-24.60) had a higher risk of RSV detection compared to children aged 37 to 60 months. Furthermore, it was found that caregivers with tertiary education had higher odds of HMPV detection (AOR: 6.91, 95% CI: 1.71-47.3).

conclusionThe detection of multiple viruses with a higher prevalence of HMPV and RSV in our study emphasises the need for a scaled-up and sustained surveillance of respiratory viruses in Ghana in the post-pandemic era. Such an establishment in respiratory virus surveillance systems in Ghana would help in the timely detection and education on viral seasonal patterns, which will inform public health responses.

Indexed as

COVID-19Respiratory Tract InfectionsVirus DiseasesChild, PreschoolCross-Sectional StudiesFemaleGhanaHumansInfantMalePrevalenceRisk FactorsVirusesChildrenCo-detectionGhanaRespiratory viruses

Identifiers

PMID40596928
PMCPMC12211473

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.