Evidence map›Paper›PMID 40596924›Full record

Observational studyBMC emergency medicine2025

Time-based tracking of temperature and humidity of emergency medical service rapid response vehicles in Qatar: a prospective observational study.

Nour Alhuda Alaghawani, Abrar Mohamed, Ahmed Makhlouf, Habib Kerkeni, Loua Al Shaikh, Guillaume Alinier, Alaaldin M Alkilany, Ousama Rachid

Abstract readObservational Study
In one paragraph

Observational study in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nour Alhuda AlaghawaniCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Abrar MohamedCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Ahmed MakhloufHamad Medical Corporation Ambulance Service, Doha, Qatar.
Habib KerkeniHamad Medical Corporation Ambulance Service, Doha, Qatar.
Loua Al ShaikhHamad Medical Corporation Ambulance Service, Doha, Qatar.
Guillaume AlinierHamad Medical Corporation Ambulance Service, Doha, Qatar.
Alaaldin M AlkilanyCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar.
Ousama RachidCollege of Pharmacy, QU Health, Qatar University, Doha, Qatar. orachid@qu.edu.qa.

Funding

Qatar National Research Fund UREP25-069-3-021Qatar University Office of Research Support QUST-2-CPH-2023-1517
6 · The paper itself

Abstract

backgroundParamedics working in emergency medical services (EMS) routinely administer life-saving medications to patients under urgent conditions. However, these medications are frequently subjected to undocumented fluctuations in environmental conditions, particularly temperature and humidity, which may lead to drug degradation and potentially compromise patient safety. In countries like the State of Qatar, known for its elevated temperatures and humidity, the environmental exposure of EMS medications stored in rapid response cars (RRCs) has not yet been systematically assessed. In this study, we aimed to evaluate the fluctuations in temperature and humidity experienced by ambulatory medications over a 12-month period.

methodsSix RRCs, each with three temperature and humidity loggers were utilized to collect real-life environmental data. Two loggers were placed in two paramedic bags stored at the back of the RRCs while a third logger was attached in the middle inside each car. Temperature and humidity readings were recorded at 10-minute intervals over 12 months for assessment. Data was then extracted using ElitechLog software, visualized using Python, and statistically analyzed. The mean kinetic temperature (MKT) was also calculated.

resultsTemperature values reached 59.1 and 65.7 °C in the bags and inside the RRC, respectively. The MKT exceeded the United States Pharmacopeia recommendations of 30 °C, and in some instances, it exceeded 50 °C. Little to no difference was observed between the two bags in each car however, greater temperature values and MKT violations were reported by the centrally located sensor inside the RRCs.

conclusionThe reported MKT violations highlight the need to develop and implement improved storage strategies for EMS medications in emergency vehicles operating in extremely hot climates. However, given that medication bags are frequently exposed to high ambient temperatures when carried outside by paramedics, storage solutions alone are insufficient to fully prevent deviations from manufacturers' recommended conditions. This underscores the importance of specialized training for paramedics on stringent medication handling protocols to minimize temperature exposure and ensure drug safety and efficacy. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

AutomobilesDrug StorageEmergency Medical ServicesHumidityTemperatureHumansProspective StudiesQatarTime FactorsAmbulancesEmergency medical servicesHumidityMean kinetic temperatureRapid response carsTemperature

Identifiers

PMID40596924
PMCPMC12211764

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.