Observational studyBMC emergency medicine2025
Non-invasive hemodynamic monitoring and cardiac preload assessment in severely injured children in the emergency department.
Observational study in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Correlation Between Hemodynamic Parameters Measured by Ultrasonic Cardiac Output Monitor and Serum Troponin I Levels in Pediatric Septic Shock Patients: A Prospective Observational Study.Open access emergency medicine : OAEM · 2026Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesThis study aimed to evaluate cardiac preload and identify early predictors of severe trauma in pediatric patients using non-invasive hemodynamic monitoring in the pediatric emergency department.
methodsA prospective cohort study was conducted at Xi'an Children's Hospital (June 2022-October 2024) with 167 patients, divided into mild (84) and severe (83) trauma groups. Non-invasive monitoring began shortly after admission, collecting parameters alongside clinical and laboratory assessments.
resultsNo significant differences in demographics or injury characteristics were found between groups. The severe trauma group had higher blood transfusion requirements (TAR) (p < 0.01). Hemodynamic parameters showed reduced pre-ejection period (PEP), left ventricular ejection time, and thoracic fluid content (t = 5.655, z = -4.368, z = -3.702; p < 0.01), indicating insufficient preload. Elevated heart rate (t = -4.127; p < 0.01) compensated for this. Reduced stroke volume index (t = 2.339, p < 0.05) and higher cardiac index (z = -1.979; p < 0.05) suggested compensation for low hemoglobin. The severe group also had elevated white blood cells, blood glucose, lactate, interleukin-6, interleukin-10, ALT, and AST (p < 0.01), while hemoglobin, fibrinogen, and albumin were decreased (p < 0.01). Logistic regression identified PEP, albumin, interleukin-6, and TAR as independent risk factors for severe trauma (p < 0.05). PEP and interleukin-6 had the highest area under the curve values (> 0.70).
conclusionsNon-invasive hemodynamic monitoring can detect early signs of insufficient preload in severe pediatric trauma, and the combination of PEP and interleukin-6 aids in severity assessment and clinical decision-making. CLINICAL
trial registrationNot applicable.
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