Evidence map›Paper›PMID 40596902›Full record

ArticleBMC medical imaging2025

Non-invasive assessment of liver function in cirrhosis using iodine density difference between the portal vein and hepatic vein on spectral CT: correlation with Child-Pugh grades.

Lu Yu, Zhengping Song, Zhoulei Li, Wen Lv, Fei Yang, Xuehua Li, Canhui Sun

Abstract read
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Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lu Yu *Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.
Zhengping Song *Department of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.
Zhoulei LiDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.
Wen LvDepartment of Radiology, The First Affiliated Hospital, Jinan University, Guangzhou, 510632, People's Republic of China.
Fei YangDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.
Xuehua LiDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China.
Canhui SunDepartment of Radiology, The First Affiliated Hospital, Sun Yat-Sen University, No. 58, Second Zhongshan Road, Yuexiu District, Guangzhou, 510080, People's Republic of China. sunch@mail.sysu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo explore the feasibility and clinical significance of assessing liver function damage in patients with post-hepatitis cirrhosis using spectral CT by measuring the iodine density difference and CT value difference between the portal vein and hepatic vein.

methodsA study was conducted involving 65 patients with post-hepatitis cirrhosis (30 with Child-Pugh grade A, 28 with grade B, and 7 with grade C) and 82 healthy controls. All underwent dual-phase enhanced spectral CT scans of the upper abdomen. Post-processing with IntelliSpace Portal software yielded iodine density (ID), 45 keV virtual monoenergetic (VMI), and conventional CT (HU) images. The mean iodine densities of the portal vein (ID

resultsThe ID

conclusionsThe iodine density difference (ID CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Hepatic VeinsIodineLiver CirrhosisPortal VeinTomography, X-Ray ComputedAdultAgedCase-Control StudiesFeasibility StudiesFemaleHumansLiverLiver Function TestsMaleMiddle AgedIodineHepatic veinIodine densityLiver cirrhosisLiver functionPortal veinSpectral CT

Identifiers

PMID40596902
PMCPMC12220438

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.