ArticleBMC medical imaging2025
Prediction of induction chemotherapy response in locoregionally advanced nasopharyngeal carcinoma based on three pretreatment non-Gaussian diffusion MRI models.
Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Precise zonal diagnosis: multi-b-value DWI model reveals differential predictors of clinically significant prostate cancer in peripheral and transition zones.Insights into imaging · 2026Article
- Evaluating the efficacy of virtual magnetic resonance elastography and continuous-time random walk models in predicting clinically significant prostate cancer.Abdominal radiology (New York) · 2026Article
- Evaluating the early therapeutic response of radiofrequency ablation in rabbit VX2 lung tumors: a comparison of four diffusion weighted imaging models.Translational lung cancer research · 2026Article
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Authors and funding
9 authors.
Funding
Abstract
objectivesTo explore the value of continuous-time random walk (CTRW), fractional order calculus (FROC), and stretched exponential model (SEM) in predicting for response to induction chemotherapy (IC) in nasopharyngeal carcinoma (NPC).
methodsThis prospective study included the NPC participants (n = 79) who underwent non-Gaussian (CTRW, FROC, and SEM) model from December 2023 to October 2024. Eight diffusion parameters, namely α
resultsParticipants enrolled in this study were classified into response group (n = 60) and non-response group (n = 19). Participants who responded well to IC had lower α
conclusionsThe developed model combining α RELEVANCE STATEMENT: We developed a logistic regression model based on pre-treatment non-Gaussian diffusion MRI parameters to reliably predict early response to induction chemotherapy in locally advanced nasopharyngeal carcinoma. This model may aid in personalizing treatment and minimizing unnecessary toxicity for non-responders.
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