Evidence map›Paper›PMID 40596883›Full record

ArticleBMC infectious diseases2025

Distribution of carbapenemase-producing and colistin resistant Acinetobacter baumannii isolates in Batna hospitals, Algeria.

Asma Bouali, Esma Bendjama, Zineb Cherak, Meriem Mennaai, Ahmed Kassah-Laouar, Jean-Marc Rolain, Lotfi Loucif

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Asma BoualiLaboratoire des Sciences Alimentaires, Institut des Sciences Vétérinaires et des Sciences Agronomiques, Université Batna 1, Batna, Algérie.
Esma BendjamaDépartement de Technologie Alimentaire, Institut des Sciences Vétérinaires et des Sciences Agronomiques, Université Batna 1, Batna, Algérie.
Zineb CherakDépartement de Microbiologie et de Biochimie, Faculté des Sciences de la Nature et de la Vie, Université Batna 2, Batna, Algérie.
Meriem MennaaiLaboratoire Central de Biologie Médicale, Centre de Lutte Contre le Cancer, Batna, Algérie.
Ahmed Kassah-LaouarCentre de Diagnostic Médical El Moustakbel, Batna, Algérie.
Jean-Marc RolainIHU Méditerranée Infection, MEPHI, Aix Marseille Université, Faculté de Médecine et de Pharmacie, Marseille, France.
Lotfi LoucifDépartement de Microbiologie et de Biochimie, Faculté des Sciences de la Nature et de la Vie, Université Batna 2, Batna, Algérie. lotfiloucif@hotmail.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to investigate the distribution and genetic determinants of carbapenemase production and colistin resistance among Acinetobacter baumannii isolates recovered from three health care facilities in the city of Batna, Algeria.

methodsA prospective study was conducted between 2021 and 2022 on 46 Acinetobacter baumannii clinical isolates, which were collected and identified using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Antibiotic susceptibility testing was performed using the disk diffusion method and colistin minimum inhibitory concentrations (MICs) were determined by broth microdilution method. Carbapenemase and colistin resistance determinants were detected by qPCR.

resultsThe 46 clinical isolates were mainly from the intensive care unit (52.17%) and the burns unit (17.39%). The strains were collected primarily from pus samples (34.78%) and blood samples (17.39%). Eleven strains were classified as colistin-resistant, with MICs ranging from 4 to 128 μg/mL. The bla

conclusionHere, we report a high prevalence of carbapenemases-producing A. baumannii isolates in Batna hospitals. Notably, this study is the first to identify A. baumannii isolates co-producing OXA-24 and NDM carbapenemases and to report the first detection of colistin-resistant A. baumannii co-producing OXA-24 and OXA-23 carbapenemases from a patient in Algeria.

Indexed as

Acinetobacter baumanniiAcinetobacter InfectionsAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasesColistinDrug Resistance, BacterialAlgeriaDrug Resistance, Multiple, BacterialFemaleHospitalsHumansMaleMicrobial Sensitivity TestsMiddle AgedProspective StudiesAnti-Bacterial AgentsBacterial Proteinsbeta-LactamasescarbapenemaseColistinAcinetobacter baumanniiAlgeriabla NDMbla OXA-23bla OXA-24

Identifiers

PMID40596883
PMCPMC12210872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.