Evidence map›Paper›PMID 40596877›Full record

Observational studyBMC anesthesiology2025

Optic nerve sheath diameter is associated with postoperative delirium in patients undergoing open heart surgery.

Aynur Kaynar, Özgür Kömürcü, Esma Bahşi, Ahmet Ozan Aydın, İlker Hasan Karal, Dilan Akyurt, Serkan Tulgar, Mustafa Süren

2 registry-linked trialsAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05942183 completednot on this map

The Relationship Between Optic Nerve Sheath Diameter and Postoperative Delirium in Open Heart Surgery

TypeobservationalSponsorSamsun UniversityRan2023 to 2024Enrolled90ConditionsDelirium, Postoperative, Cardiac Disease, Cardiac Valve DiseaseArmsONSD
NCT07249047 nanot yet recruitingnot on this mapstarted 2026, after this paper: background citation

Correlation Between Optic Nerve Sheath Diameter Measured by Ultrasound and Delirium in Cardiac Surgery

TypeinterventionalSponsorLondon Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph'sRan2026 to 2027Enrolled300ConditionsPostoperative DeliriumArmsOptic nerve sheath diameter (ONSD) ultrasound
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aynur KaynarDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.
Özgür KömürcüDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey. zgrkom@gmail.com.
Esma BahşiDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.
Ahmet Ozan AydınDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.
İlker Hasan KaralDepartment of Cardiac and Vascular Surgery, Samsun University Faculty of Medicine, Samsun, Turkey.
Dilan AkyurtDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.
Serkan TulgarDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.
Mustafa SürenDepartment of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, İlkadım, TR55090, Samsun, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased intracranial pressure is a possible cause of postoperative delirium in open heart surgery patients. Optic nerve sheath diameter is a non-invasive measurement method used to monitor intracranial pressure changes. The authors suggested in this study that optic nerve sheath diameter monitoring could identify patients at risk of postoperative delirium.

methodThis prospective observational study was conducted by evaluating data from 90 patients undergoing open heart surgery. Optic nerve sheath diameter in patients was recorded before and after anesthesia induction, before and after cardiopulmonary bypass, and after intensive care transfer. Postoperative delirium was evaluated with the Confusion Assessment Method for the Intensive Care Unit scale.

resultsThe study was completed with 90 patients and postoperative delirium was observed in 20 of the patients (22.2%). Optic nerve sheath diameter (OR, 5.787; 95% CI, 1.489-22.496; P = 0.011), history of alcohol use (OR, 6.032; 95% CI, 1.052-34.604; P = 0.044), and EuroSCORE II (OR, 3.090; 95% CI, 1.453-6.571; P = 0.003) was associated with postoperative delirium.

conclusionsOptic nerve sheath diameter measured by ultrasonography is associated with postoperative delirium. The increase in optic nerve sheath diameter can be used predictively for postoperative delirium in open heart surgery.

trial registrationSamsun University Samsun Training and Research Hospital, following ethics committee approval (Samsun University clinical research ethics committee (KAEK) 2023 11/7) and Clinical Trials (NCT05942183 / 05.09.2024) registration.

Indexed as

Cardiac Surgical ProceduresDeliriumEmergence DeliriumOptic NervePostoperative ComplicationsAgedFemaleHumansIntracranial PressureMaleMiddle AgedProspective StudiesUltrasonographyAnesthesiaOpen heart surgeryOptic nerve sheath diameterPostoperative deliriumUltrasonography

Identifiers

PMID40596877
PMCPMC12210449

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.