Evidence map›Paper›PMID 40596874›Full record

Observational studyBMC nephrology2025

Peritoneal dialysis catheter insertion in patients with obesity: a cohort study and single centre approach to increasing uptake.

Walker Andrew, Corr Michael, Conroy Daniel, McDaid James, McGrogan Damian, Fogarty Damian, O'Neil Stephen

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Walker AndrewRegional Nephrology & Transplant Unit-Belfast Health and Social Care Trust, Belfast, UK.
Corr MichaelCentre for Public Health, Institute of Clinical Sciences B, Royal Victoria Hospital, Belfast, BT12 6BA, UK. Michael.corr@qub.ac.uk.
Conroy DanielInterventional Radiology Department, Belfast Health and Social Care Trust, Belfast, UK.
McDaid JamesRegional Nephrology & Transplant Unit-Belfast Health and Social Care Trust, Belfast, UK.
McGrogan DamianRegional Nephrology & Transplant Unit-Belfast Health and Social Care Trust, Belfast, UK.
Fogarty DamianRegional Nephrology & Transplant Unit-Belfast Health and Social Care Trust, Belfast, UK.
O'Neil StephenRegional Nephrology & Transplant Unit-Belfast Health and Social Care Trust, Belfast, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe global prevalence of obesity in patients with end-stage kidney disease requiring kidney replacement therapy is rising. While peritoneal dialysis (PD) offers advantages for many patients, its use in those with obesity has been historically limited due to concerns about catheter insertion-related complications, mechanical issues, and infection risk. This study aimed to evaluate PD catheter patency, infection rates, and modality outcomes in obese and non-obese patients to inform best practices and guide programme expansion.

methodsThis single-region observational study analysed outcomes from 157 patients who underwent PD catheter insertion between 2020 and 2023 at the Northern Ireland Regional Nephrology and Transplant Centre. Patients were classified as obese (BMI ≥ 30, n = 44) or non-obese (BMI < 30, n = 113). Laparoscopic and percutaneous catheter insertion techniques were used, and primary outcomes included catheter patency (primary, primary assisted, secondary) and infection rates (exit site infection, tunnel infection, peritonitis) 1-year post-insertion. Kaplan-Meier survival analysis and descriptive statistics were applied to compare outcomes between groups.

resultsPatency rates were high in both groups, with no significant differences: primary patency was 88% in non-obese patients and 80% in obese patients (p = 0.13). Similarly, primary assisted patency was 94% versus 89% (p = 0.26), and secondary patency was 96% versus 89% (p = 0.11). Patency and infection rates remained within standards set in ISPD guidelines for both groups, although obese patients showed a non-significant trend toward higher peritonitis rates (0.09). Transfer to haemodialysis occurred more frequently in the obese group (34% vs. 19%, p = 0.06). Mortality rates were comparable (9% non-obese, 6% obese).

conclusionsThis study demonstrates that, with appropriate surgical techniques and periprocedural care, obese patients can achieve PD outcomes comparable to those of non-obese individuals. These findings challenge the traditional reluctance to offer PD to obese patients and advocate for the expansion of PD programs to include this growing demographic. CLINICAL TRIAL NUMBER: Not Applicable.

Indexed as

CatheterizationCatheters, IndwellingKidney Failure, ChronicObesityPeritoneal DialysisAdultAgedCatheter-Related InfectionsCohort StudiesFemaleHumansLaparoscopyMaleMiddle AgedPeritonitisCatheterKidney replacement therapyObesityPeritoneal dialysisPeritonitis

Identifiers

PMID40596874
PMCPMC12211634

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.