ArticleBMC infectious diseases2025
Virulence and biological characteristics of Talaromyces wortmannii isolated from deep-seated dermatomycosis by in vitro and in vivo evaluation.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Interactions ofInternational journal of molecular sciences · 2025Article
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Authors and funding
5 authors.
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Abstract
backgroundTalaromyces wortmannii is a ubiquitous saprophytic fungus found in soil, plants, and marine organisms. Infections caused by T. wortmannii in humans are rarely reported, however, a recent case of skin mycosis attributed to this fungus highlights its potential to cause infections under certain conditions. Therefore, studying the biological characteristics of T. wortmannii is crucial for the prevention and control of dermatomycosis.
methodsT. wortmannii was incubated on different medium and at various temperatures, gathered pertinent data on colony growth and conduct an analysis of its growth characteristics. The Sensititre YeastOne
resultsThe characteristic of T.wortmannii included septate hyphae, occasionally fragmented with varying diameters. Velvety colonies with dense sporulation were observed, grow fastest at 32 °C and displayed a radial growth pattern with a centrally elevated morphology and a slightly depressed margin. The MICs of amphotericin B, itraconazole, posaconazole and voriconazole were relatively low, suggesting potential clinical efficacy. A greater number of deaths occurred at higher inoculum levels. Both the T.wortmannii clinical strain F22-1-C5 and standard strain CGMCC3.17703 exhibits virulence towards the larvae.
conclusionsT. wortmannii can cause human infections. Amphotericin B, itraconazole, posaconazole, and voriconazole may be effective for treatment of such infectoins.
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