Evidence map›Paper›PMID 40596863›Full record

Trial reportBMC anesthesiology2025

Effects of two different partial pressure of end-tidal carbon dioxide levels on cardiac function in patients undergoing carotid endarterectomy: a randomized controlled trial.

Pei Wang, Chuanyu Liang, Yi An, Lixia Li, Zhongjia Li, Xuefei Jia, Hongyi Song, Tianlong Wang, Lei Zhao

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC anesthesiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Pei WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Chuanyu LiangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Yi AnDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lixia LiDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Zhongjia LiDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Xuefei JiaDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Hongyi SongDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Tianlong WangDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lei ZhaoDepartment of Anesthesiology, Xuanwu Hospital, Capital Medical University, Beijing, China. zhaoalei@sina.com.

Funding

Beijing Municipal Administration of Hospitals Incubating Program PX2022033National Natural Science Foundation of China 62376168
6 · The paper itself

Abstract

backgroundMost patients undergoing carotid endarterectomy (CEA) are complicated with coronary artery disease and at high risk for cardiovascular events. This study aims to regulate cerebral blood flow by adjusting the level of partial pressure of end-tidal carbon dioxide (P

methodsIn this randomized controlled trial, we randomly assigned 44 patients to receive a P

resultsSixty nine patients were finally included, 34 patients in the control group and 35 patients in the intervention group. No significant differences were found between the groups for E/e' (P = 0.614), GLS (P = 0.231), or the incidence of postoperative complications (P > 0.05). The dMAP of patients during carotid artery occlusion in the intervention group was lower than that in the control group (9.1% ±10.5% vs 14.3% ±9.2%, P < 0.05).

conclusionsP

trial registrationThis trial was registered on the Chinese Clinical Trial Registry ( http://www.chictr.org.cn , ChiCTR2100049772; August 9, 2021).

Indexed as

Carbon DioxideEndarterectomy, CarotidAgedCerebrovascular CirculationFemaleHumansMaleMiddle AgedPartial PressurePostoperative ComplicationsCarbon DioxideCarotid endarterectomyE/e’Myocardial strainPartial pressure of end-tidal carbon dioxide

Identifiers

PMID40596863
PMCPMC12210760

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.