Evidence map›Paper›PMID 40596849›Full record

ArticleBMC plant biology2025

Integrated analyses of transcriptome, metabolome and floral B-class genes reveal sexual dimorphism in Eucommia ulmoides.

Xianzhi Zhang, Wenliang He, Xinyi Wang, Yongquan Li, Zhaojun Liu, Wencai Wang

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Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xianzhi ZhangCollege of Horticulture and Landscape Architecture, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
Wenliang HeCollege of Horticulture and Landscape Architecture, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
Xinyi WangCollege of Horticulture and Landscape Architecture, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
Yongquan LiCollege of Horticulture and Landscape Architecture, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China.
Zhaojun LiuBiological Breeding Laboratory, Xinjiang Academy of Agricultural Sciences, Urumqi, 830091, China. lzjdeyouxiang@126.com.
Wencai WangCollege of Horticulture and Landscape Architecture, Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, China. wencaiwang@gzucm.edu.cn.

Funding

Innovation Project for Forestry Science and Technology in Guangdong 2024KJCX004Rural Revitalization Project of Guangdong Province KTP20240155Scarce and Quality Economic Forest Engineering Technology Research Center 2022GCZX002
6 · The paper itself

Abstract

Eucommia ulmoides is a dioecious plant species that has been widely utilized as an important traditional Chinese medicine. To investigate sexual dimorphism and its underling molecular basis in E. ulmoides, we conducted an integrated analysis of transcriptomic and metabolomic data, alongside functional gene studies, for the first time. The results revealed that 8,811 (43.72%) of genes expressed in flowers were sex-biased genes, significantly more than the 116 (0.078%) identified in leaves. Among these, two male-biased and four female-biased genes consistently expressed in both flowers and leaves were identified, including two B-class floral organ identity genes, i.e. AP3-like EuMADS39 and PI-like EuMADS28. Additionally, 123 differentially abundant metabolites were detected between male and female flowers. Functional analyses demonstrated that protein EuMADS39 and EuMADS28 are both localized in the nucleus and capable of forming a protein complex. Transgenic Arabidopsis plants co-expressing EuMADS39 and EuMADS28 exhibited an increased number of stamens (7) compared to wild-type plants (6), confirming their roles as B-class genes in the development of unisexual flowers in E. ulmoides. In summary, this study uncovered the sexual dimorphisms in gene expression and metabolite profiles of E. ulmoides, and validated the role of B-class genes in sexual dimorphism of E. ulmoides. Clinical trial number Not applicable.

Indexed as

EucommiaceaeFlowersMetabolomeTranscriptomeArabidopsisGene Expression ProfilingGene Expression Regulation, PlantGenes, PlantPlant LeavesPlant ProteinsPlants, Genetically ModifiedSex CharacteristicsPlant ProteinsEucommia ulmoidesFloral B-class genesGene expressionSecondary metabolitesSexual dimorphism

Identifiers

PMID40596849
PMCPMC12211642

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