Evidence map›Paper›PMID 40596774›Full record

ArticleJournal of cardiovascular electrophysiology2025

Left Atrial Function and Strain Assessed by Three-Dimensional Echocardiography as Factors Associated With Atrial Fibrillation Recurrence After Pulmonary Vein Ablation.

Andrea P Maldonado-Tenesaca, Elias N Andrade Cuellar, Froylan D Martínez-Sánchez, Rocio Aceves-Millan, Juan Carlos Solis-Gómez, Jose J I Y Zamora-Diaz, Martin R Cedillo-Urbina, Carlos H Ixcamparij-Rosales, Rogelio Robledo-Nolasco

Abstract read
In one paragraph

Article in Journal of cardiovascular electrophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrea P Maldonado-TenesacaEchocardiography Laboratory, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Elias N Andrade CuellarCardiac Electrophysiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Froylan D Martínez-SánchezFacultad de Medicina, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico.ORCID 0000-0002-2719-1105
Rocio Aceves-MillanEchocardiography Laboratory, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Juan Carlos Solis-GómezCardiac Electrophysiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Jose J I Y Zamora-DiazDepartment of Cardiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Martin R Cedillo-UrbinaDepartment of Cardiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Carlos H Ixcamparij-RosalesDepartment of Cardiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.
Rogelio Robledo-NolascoCardiac Electrophysiology, Centro Médico Nacional 20 de Noviembre ISSSTE, Mexico City, Mexico.

Funding

The authors received no specific funding for this work.
6 · The paper itself

Abstract

introductionRecurrence of atrial fibrillation (AF) after pulmonary vein isolation (PVI) remains a major clinical challenge. Left atrial (LA) remodeling contributes to recurrence, but its predictive value is still under investigation. This study aimed to assess LA morphology, function, and strain using three-dimensional (3D) echocardiography and determine their association with AF recurrence. METHODS AND

resultsThis prospective, single-center study included 119 patients with paroxysmal or persistent AF who underwent radiofrequency or cryoballoon ablation. Six months after the procedure, an echocardiographic assessment was performed, evaluating LA volumes, reservoir, conduit, booster pump function, global longitudinal strain (GLS), and LA ejection fraction (LAEF). AF recurrence occurred in 26.1% of patients. Patients with recurrence had larger LA dimensions (p < 0.01) and reduced GLS, LAEF, and peak atrial longitudinal strain (PALS) (p < 0.001). Multivariate analysis identified GLS > -13.5% (OR = 3.495, p < 0.001) and LAEF < 27.5% (OR = 0.857, p < 0.001) as independent predictors of recurrence. ROC analysis confirmed their strong discriminatory ability (AUC: 0.941 and 0.812, respectively).

conclusionLA remodeling and dysfunction are key predictors of AF recurrence after PVI. Reduced GLS and LAEF and increased LA size were independently associated with recurrence, supporting their role in risk stratification and personalized management. Incorporating 3D echocardiographic and strain-based analysis may enhance postablation surveillance and therapeutic decision-making.

Indexed as

Atrial FibrillationAtrial Function, LeftAtrial RemodelingCatheter AblationCryosurgeryEchocardiography, Three-DimensionalPulmonary VeinsAction PotentialsAgedFemaleHeart RateHumansMaleMiddle AgedPredictive Value of TestsProspective Studiesatrial fibrillationatrial strainleft atriumpulmonary vein ablationthree‐dimensional echocardiography

Identifiers

PMID40596774
PMCPMC13034725

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.