Evidence map›Paper›PMID 40596663›Full record

ArticleScientific reports2025

Accelerating infectious wound healing through bacterial cellulose/ag composite film enriched with GM-CSF.

Bilin Zhang, Zhifeng Huang, Tian Guo, Jingchen Jing, Yunzhi Dang

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Bilin ZhangDepartment of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710086, China.
Zhifeng HuangDepartment of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710086, China.
Tian GuoDepartment of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710086, China.
Jingchen JingDepartment of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710086, China.
Yunzhi DangDepartment of Radiation Oncology, Shaanxi Provincial People's Hospital, Xi'an, 710086, China. dangyunzhi@xiyi.edu.cn.

Funding

National Natural Science Foundation of China 82203521
6 · The paper itself

Abstract

Infectious wounds have increasingly become a significant clinical challenge due to their high incidence and suboptimal treatment outcomes. An ideal wound dressing would be a smart, in situ-formed material with exceptional antibacterial properties and the ability to eliminate biofilms, thereby facilitating effective wound closure. Bacterial cellulose (BC) is an attractive candidate for wound healing applications due to its unique characteristics, including high water retention, flexibility, biocompatibility, and substantial adsorption capacity. However, its limited antibacterial activity constrains its use in skin wound healing. In this work, we employed BC as a matrix material, silver nanoparticles (Ag) as antibacterial agents, and granulocyte-macrophage colony-stimulating factor (GM-CSF) as a cell growth-promoting factor to enhance the healing of infected chronic wounds. The resulting BC/Ag/GM-CSF composite demonstrated excellent blood compatibility, cell compatibility, and antibacterial efficacy. Additionally, the BC/Ag/GM-CSF composite film shows promising potential as a wound dressing for both acute and chronic infectious wounds.

Indexed as

Anti-Bacterial AgentsCelluloseGranulocyte-Macrophage Colony-Stimulating FactorSilverWound HealingWound InfectionAnimalsBandagesBiofilmsHumansMetal NanoparticlesMiceAnti-Bacterial AgentsCelluloseGranulocyte-Macrophage Colony-Stimulating FactorSilverAntimicrobial activityBacterial celluloseGM-CSFSilver nanoparticleWound healing

Identifiers

PMID40596663
PMCPMC12219182

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.