Evidence map›Paper›PMID 40596621›Full record

ArticleScientific reports2025

Muscle-Driven prognostication in gastric cancer: A multicenter deep learning framework integrating Iliopsoas and erector spinae radiomics for 5-Year survival prediction.

Yuan Hong, Peng Zhang, Zhijun Teng, Kang Cheng, Zimo Zhang, Yixian Cheng, Guodong Cao, Bo Chen

Abstract readMulticenter Study
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Developing and validating a combined model with CT-based paraspinal muscle radiomics and clinical features to predict residual low back pain after percutaneous kyphoplasty.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yuan HongDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China.
Peng ZhangDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China.
Zhijun TengDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China.
Kang ChengDepartment of The First Clinical Medical College, Anhui Medical University, Hefei, 230022, China.
Zimo ZhangDepartment of The First Clinical Medical College, Anhui Medical University, Hefei, 230022, China.
Yixian ChengDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China.
Guodong CaoDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China. ayfycgd@163.com.
Bo ChenDepartment of General Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, 218 Jixi Road, China. chenbo831116@163.com.

Funding

National Natural Science Foundation of China 82403333the Graduate Student Research and Practice Innovation Program of Anhui Medical University YJS20230080
6 · The paper itself

Abstract

This study developed a 5-year survival prediction model for gastric cancer patients by combining radiomics and deep learning, focusing on CT-based 2D and 3D features of the iliopsoas and erector spinae muscles. Retrospective data from 705 patients across two centers were analyzed, with clinical variables assessed via Cox regression and radiomic features extracted using deep learning. The 2D model outperformed the 3D approach, leading to feature fusion across five dimensions, optimized via logistic regression. Results showed no significant association between clinical baseline characteristics and survival, but the 2D model demonstrated strong prognostic performance (AUC ~ 0.8), with attention heatmaps emphasizing spinal muscle regions. The 3D model underperformed due to irrelevant data. The final integrated model achieved stable predictive accuracy, confirming the link between muscle mass and survival. This approach advances precision medicine by enabling personalized prognosis and exploring 3D imaging feasibility, offering insights for gastric cancer research.

Indexed as

Deep LearningParaspinal MusclesPsoas MusclesStomach NeoplasmsAgedFemaleHumansMaleMiddle AgedPrognosisRadiomicsRetrospective StudiesTomography, X-Ray ComputedDeep learningGastric cancerRadical gastrectomySarcopenia

Identifiers

PMID40596621
PMCPMC12215766

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.