SynthesisScientific reports2025
Prognostic value of the C-reactive protein to albumin ratio in patients with stroke: a meta-analysis.
Synthesis in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Incremental Prognostic Value of the C-Reactive Protein-to-Albumin Ratio Beyond a Parsimonious Clinical Reference Model in Critically Ill Patients with Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2026Article
- Article
- Association of lipoprotein(a) and composite inflammatory indices with functional outcomes in acute ischemic stroke: a prospective cohort study.Lipids in health and disease · 2026Article
- Stroke-Associated Pneumonia and Impaired Functional Recovery After Stroke: The Role of Nutritional-Inflammatory Factors.Advances in respiratory medicine · 2026Article
- Article
- Comparative screening performance and multicenter validation of novel inflammatory biomarkers (NLR, SII, and CAR) for risk stratification of diabetic foot ulcer in patients with type 2 diabetes mellitus.Frontiers in medicine · 2026Article
- The Association Between C-Reactive Protein-to-Albumin Ratio and in-Hospital Mortality in Patients withJournal of inflammation research · 2026Article
- Integrating Inflammation and Lipid Metabolism Biomarkers for Early Risk Stratification in Acute Cerebral Infarction: A Nomogram-Based Approach.Mediators of inflammation · 2026Article
- The Ratio Paradox in Stroke Prognosis: Abundant Evidence, Absent Utility.Translational stroke research · 2025Article
- Predictive Value of C-Reactive Protein/Albumin Ratio (CAR) for Malnutrition and Sarcopenia in Acute Ischemic Stroke Patients.Journal of clinical medicine · 2025Article
- Article
- Association between C-reactive protein/albumin ratio and mortality in older Japanese patients with post-stroke dysphagia.Frontiers in neurology · 2025Article
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
Stroke poses a significant mortality threat and frequently results in survivors experiencing varying degrees of residual disability. The objective of this meta-analysis was to elucidate the association between C-reactive protein-to-albumin ratio (CAR) and prognosis in patients with stroke. We searched the databases of PubMed, Embase, the Cochrane Library, and CNKI for relevant studies up to 26th January 2024. The quality of the included studies was evaluated using the Newcastle Ottawa Quality Assessment Scale (NOS). Pooled odds ratios (OR) with 95% confidence intervals (CI) were calculated for the association between CAR and poor functional outcomes and mortality. A total of nine studies with 2954 patients were included. The pooled results demonstrated that elevated CAR was associated with poor functional outcomes in patients with stroke (OR: 2.24; 95% CI: 1.81-2.78; P < 0.00001). Similarly, elevated CAR was associated with mortality in patients with stroke (OR: 2.11; 95% CI: 1.51-2.94; P < 0.0001). CAR has prognostic value for poor functional outcomes and mortality in patients with stroke.
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