ArticleScientific reports2025
Nomogram prediction of overall survival in patients with bone metastases from hepatocellular carcinoma: a SEER-based retrospective cohort study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- A rare presentation of hepatocellular carcinoma: Cervical and destructive thoracic paravertebral masses.Radiology case reports · 2026Article
- Cancer-specific survival patterns in patients with bone metastasis: a registry-based analysis of 13,742 patients.Scientific reports · 2026Article
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13 authors.
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Abstract
This study aimed to construct a nomogram for predicting overall survival in patients with bone metastases (BM) from hepatocellular carcinoma (HCC), leveraging data from the Surveillance, Epidemiology, and End Results (SEER) database spanning the period from 2010 to 2015. The patient cohort was randomly partitioned into a training set (n = 338) and a validation set (n = 145). Kaplan-Meier analysis and multivariate Cox proportional hazards regression identified marital status, liver surgery, and radiotherapy/chemotherapy as significant prognostic factors (P ≤ 0.05), which were subsequently integrated into the nomogram. The nomogram exhibited a concordance index of 0.72 (95% confidence interval: 0.70-0.75) and demonstrated robust calibration between predicted and observed survival rates. This nomogram has the potential to accurately forecast prognosis and assist clinicians in formulating appropriate treatment strategies for patients with HCC bone metastasis.
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