Evidence map›Paper›PMID 40596297›Full record

ArticleScientific reports2025

Systematic assessment of bone and soft tissue tumors on whole-body CTs of 45 mummies from ancient Egypt.

Stephanie Panzer, Klaus Wörtler, Alice Paladin, Stephanie Zesch, Wilfried Rosendahl, Katherine D van Schaik, M Linda Sutherland, James D Sutherland, Klaus Hergan, Randall C Thompson and 1 more

Abstract readHistorical Article
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stephanie PanzerDepartment of Radiology, University Hospital Salzburg, Paracelsus Medical University, Müllner-Hauptstraße 48, 5020, Salzburg, Austria. stephanie.panzer@pmu.ac.at.
Klaus WörtlerDepartment of Radiology, Klinikum Rechts der Isar, Technische Universität München, Ismaninger Straße 22, 81675, Munich, Germany.
Alice PaladinInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.
Stephanie ZeschGerman Mummy Project, Reiss-Engelhorn-Museen, Museum Weltkulturen D5, 68159, Mannheim, Germany.
Wilfried RosendahlGerman Mummy Project, Reiss-Engelhorn-Museen, Museum Weltkulturen D5, 68159, Mannheim, Germany.
Katherine D van SchaikProgram in Health Over Time, Department of Radiology/Department of Classical Studies, Medical Center North, Vanderbilt University, 1161 21st Ave. South, Nashville, TN, 37232, USA.
M Linda SutherlandMemorialCare Health System, 18035 Brookhurst Street, Fountain Valley, CA, 92708, USA.
James D SutherlandMemorialCare Health System, 18035 Brookhurst Street, Fountain Valley, CA, 92708, USA.
Klaus HerganDepartment of Radiology, University Hospital Salzburg, Paracelsus Medical University, Müllner-Hauptstraße 48, 5020, Salzburg, Austria.
Randall C ThompsonSaint Luke's Mid America Heart Institute, University of Missouri-Kansas City, 4330 Wornall Road, Kansas City, MO, 64111, USA.
Albert R ZinkInstitute for Mummy Studies, Eurac Research, Viale Druso 1, 39100, Bolzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a growing interest in the antiquity of cancer and ongoing discussion of the apparent scarcity of malignant tumors in ancient human remains, especially those of soft tissues. We systematically assessed bone and soft tissue tumors on 45 whole-body computed tomography (CT) scans of ancient Egyptian mummies. In one of 45 cases (2%), malignant skeletal disease (probably skeletal metastases) was detected. In five of 45 cases (11%), probably malignant soft tissue masses were identified. The soft tissue masses showed distinct margins, various internal structures, and higher densities compared to preserved adjacent soft tissues. In the two cases with intra-abdominal soft tissue masses, no preserved original organs were detectable. In conclusion, malignant tumors, even those of soft tissues are detectable on CT images of ancient Egyptian mummies. The recognizability, CT characteristics, and frequency of soft tissue tumors represent new knowledge and offer a novel approach for the field of paleo-oncology.

Indexed as

Bone NeoplasmsMummiesSoft Tissue NeoplasmsTomography, X-Ray ComputedAdultEgyptEgypt, AncientFemaleHistory, AncientHumansMaleMiddle AgedPaleopathologyWhole Body ImagingYoung AdultCancerCarcinomaMetastaticNeoplasmPaleopathologyPaleoradiology

Identifiers

PMID40596297
PMCPMC12215712

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.