Evidence map›Paper›PMID 40596181›Full record

ArticleScientific reports2025

Relationship between intraocular pressure and pulmonary function.

Ryo Terauchi, Kota Fukai, Shota Fujimoto, Kyoko Ito, Tomohiro Kato, Kiminori Kato, Masayuki Tatemichi, Jun Araya, Yoshiaki Kabata, Tadashi Nakano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ryo Terauchi *Department of Ophthalmology, The Jikei University School of Medicine, 3- 25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan. r.terauchi0813@gmail.com.
Kota Fukai *Department of Preventive Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, 259-1193, Kanagawa, Japan.
Shota FujimotoDivision of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Kyoko ItoCentre for Preventive Medicine, The Jikei University School of Medicine, 3- 25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Tomohiro KatoCentre for Preventive Medicine, The Jikei University School of Medicine, 3- 25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Kiminori KatoDepartment of Prevention of Noncommunicable Diseases and Promotion of Health Checkup, Niigata University Graduate School of Medical and Dental Sciences, 1-757 Asahimachi-dori, Chuo-ku, Niigata, 951-8510, Japan.
Masayuki TatemichiDepartment of Preventive Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, 259-1193, Kanagawa, Japan.
Jun ArayaDivision of Respiratory Diseases, Department of Internal Medicine, The Jikei University School of Medicine, 3-25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Yoshiaki KabataDepartment of Ophthalmology, The Jikei University School of Medicine, 3- 25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.
Tadashi NakanoDepartment of Ophthalmology, The Jikei University School of Medicine, 3- 25-8 Nishi-shinbashi, Minato-ku, Tokyo, 105-8461, Japan.

Funding

Japan Society for the Promotion of Science 24K21131
6 · The paper itself

Abstract

We aimed to investigate the association between respiratory function and intraocular pressure (IOP). We included the Jikei and Japan Ningen Dock Study (JNDS) datasets that included data from 10,361 (50.3 ± 11.0 years) and 283,199 (51.7 ± 10.3 years) participants, respectively. IOP was measured using non-contact tonometry, and respiratory function was assessed using spirometry, focusing on the forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) ratio, percent predicted values of FEV1 (ppFEV1), and percent predicted values of FVC (ppFVC). The relationship between respiratory function indices and IOP was assessed using multiple linear regression. The mean IOP was 12.7 ± 2.8 and 13.3 ± 2.9 mmHg in the Jikei and JNDS datasets, respectively, with a significant positive linear correlation between FEV1/FVC and IOP (β = 0.020, 95% confidence interval [CI]: 0.011 - 0.029, P < 0.001 in the Jikei dataset; β = 0.015, 95% CI: 0.013 - 0.016, P < 0.001 in the JNDS dataset). Compared with healthy individuals, 505 and 2,228 participants with FEV1/FVC < 70% (Jikei dataset) and FEV1/FVC < 60% (JNDS dataset) had lower IOPs of 0.641 (95% CI: 0.286 - 0.996, P < 0.001) mmHg and 0.888 (95% CI: 0.729 - 1.047, P < 0.001) mmHg, respectively. Both ppFEV1 and ppFVC showed no association with IOP. This possible association between obstructive ventilatory disorders and IOP suggests the importance of considering respiratory function in IOP management.

Indexed as

Intraocular PressureLungAdultAgedFemaleForced Expiratory VolumeHumansJapanMaleMiddle AgedRespiratory Function TestsSpirometryTonometry, OcularVital CapacityBig dataForced expiratory volume in 1 secondForced vital capacityIntraocular pressureObstructive ventilatory disorderSpirometry

Identifiers

PMID40596181
PMCPMC12219144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.