Evidence map›Paper›PMID 40596118›Full record

ArticleScientific reports2025

Biotransformation of medicarpin from homopterocarpin by Aspergillus niger and its biological characterization.

Dwi Kusuma Wahyuni, Sumrit Wacharasindhu, Wichanee Bankeeree, Hunsa Punnapayak, Sastia Prama Putri, Sehanat Prasongsuk

Erratum issuedAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Dwi Kusuma WahyuniPlant Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Sumrit WacharasindhuDepartment of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Wichanee BankeereePlant Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Hunsa PunnapayakPlant Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand.
Sastia Prama PutriDepartment of Biotechnology, Graduate School of Engineering, Osaka University, Osaka, 5650871, Japan.
Sehanat PrasongsukPlant Biomass Utilization Research Unit, Department of Botany, Faculty of Science, Chulalongkorn University, Bangkok, 10330, Thailand. sehanat.p@chula.ac.th.

Funding

Second Century Fund (C2F) of Chulalongkorn University No. 64.310/0617/2567
6 · The paper itself

Abstract

The objective of this study was to convert homopterocarpin derived from Pterocarpus macrocarpus Kurz. heartwood to medicarpin using Aspergillus niger (strain UI X-172) and assess its antioxidant, antiplasmodial, and anticancer activities in silico and in vitro. This study highlighted biotransformation of homopterocarpin to medicarpin via demethylation. Medicarpin demonstrated antioxidant activity against 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS, IC

Indexed as

Aspergillus nigerAntimalarialsAntineoplastic AgentsAntioxidantsBiotransformationCell Line, TumorHumansMolecular Docking SimulationPlasmodium falciparumAntimalarialsAntineoplastic AgentsAntioxidantsAspergillus NigerBiological propertiesBiotransformationHomopterocarpinMedicarpin

Identifiers

PMID40596118
PMCPMC12215371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.