Evidence map›Paper›PMID 40596071›Full record

ArticleScientific reports2025

Metacognitive deficits drive depression through a network of subjective and objective cognitive functions.

Yuting Zhan, Xu Ding

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuting ZhanDepartment of Psychology, School of Education and Teaching, Ningxia University, Yinchuan, 750021, China.
Xu DingSchool of Nursing, Shandong Academy of Medical Sciences, Shandong First Medical University, Shandong Province, Tai'an City, 271016, China. evelynzhanyuting@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the relationship between depression and cognitive dysfunction has been extensively documented, research examining the intermediary role of metacognitive processes remains surprisingly limited. This study employed advanced network analytical techniques to elucidate the complex interrelationships between metacognitive beliefs, depressive symptomatology, subjective cognitive complaints (SCCs), and objective cognitive performance in clinical and non-clinical populations. Using a rigorously selected sample of participants with major depressive disorder (MDD; n = 146) and demographically matched controls (n = 138), we constructed regularized partial correlation networks to identify central nodes and bridge pathways. Results revealed that negative metacognitive beliefs specifically beliefs about uncontrollability and danger of thoughts-demonstrated the highest centrality indices (strength) and formed critical bridge connections between depressive symptoms and SCCs. Importantly, the network architecture differed significantly between MDD and control groups (Network Comparison Test: M = 0.28, p = .003), with the MDD network exhibiting stronger connectivity between metacognitive nodes and subjective cognitive complaints (∆edge = 0.31, p < .01). Longitudinal analyses utilizing graphical vector autoregression models (n = 167) demonstrated that changes in metacognitive beliefs temporally preceded alterations in both depressive symptoms (β = 0.34, p < .001) and subjective cognitive complaints (β = 0.29, p < .01), independent of objective cognitive performance. These findings provide compelling evidence for the metacognitive model of depression and suggest that interventions targeting maladaptive metacognitive beliefs may effectively address both mood symptoms and subjective cognitive dysfunction, even in the absence of objective cognitive impairment.

Indexed as

CognitionCognitive DysfunctionDepressionMajor Depressive DisorderMetacognitionAdultCase-Control StudiesFemaleHumansMaleMiddle AgedCognitive dysfunctionDepressionMetacognitionNetwork analysisSubjective cognitive complaints

Identifiers

PMID40596071
PMCPMC12218031

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.