ArticleScientific reports2025
Experimental and CFD analysis of flow impediments and encrustation in ureteral stents using in vitro urinary tract model.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
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- A 3D non-hydrostatic model for simulating coastal wave transformations: shoaling, diffraction, and refraction.Scientific reports · 2025Article
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Authors and funding
9 authors.
Funding
Abstract
A significant challenge for urological treatment is caused by encrustation that can obstruct urinary drainage. We analyzed the rate of encrustation formation for the initial three weeks in Conventional Double J Stent (CDJS), Renovated Double J Stent (RDJS), and Single J Stent (SJS) under patient-specific control conditions (37 °C, pH 7.8, 60 mL/hr., 50% stenosis). A conceptually designed in vitro urinary tract model representing the kidney, ureter and bladder model is used where the inlet flow rate is controlled with a peristaltic pump, and when the bladder is filled with artificial urine (AU), it is emptied manually, and the time is measured to calculate flow impediments. Stents have been removed from the tract after 21 days to measure mass and scanning electron microscope (SEM) analysis. A Computational Fluid Dynamics (CFD) analysis has been done to show the velocity profile and wall shear stress (WSS) of stents. RDJS has shown the highest flow rate and stable flow performance from the experiment, and SJS exhibited the lowest encrustation with a mass increase of 0.025 g compared to RDJS (0.053 g) and CDJS (0.057 g). The SEM image showed encrustation covered 10.37% of the SJS significantly lower than RDJS (13.04%) and CDJS (13.52%) near the stenosis side holes. The research evidence on SJS demonstrates the least encrustation of SJS stenosis region is further validated through the simulation result which showed a higher wall shear stress (10.4 mPa) for SJS at that location. SJS should be used for short durations for high-risk patients and RDJS for better flow maintenance, which indicates that stent selection should focus on improving the patient's outcomes.
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