ArticleNPJ biofilms and microbiomes2025
Microfluidics unveils role of gravity and shear stress on Pseudomonas fluorescens motility and biofilm growth.
Article in NPJ biofilms and microbiomes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed.
- The biofilm detachment modes and mechanisms in porous media.Biodegradation · 2026Review
- Sculpting Microbial Microenvironments: Spatiotemporal Control via Programmable Electrochemical Gradients.Journal of the American Chemical Society · 2026Review
- Interspecies electron transfer of mixed-species biofilms in microbial corrosion of metals: mechanisms and mitigation strategies.World journal of microbiology & biotechnology · 2025Review
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Authors and funding
3 authors.
Funding
Abstract
Biofilm proliferation in confined environments is a challenge in biomedical, industrial, and space applications. Surfaces in contact with fluids experience varying bulk stresses due to flow and gravity, factors often overlooked in biofilm studies. This research quantifies the combined effect of gravity and shear stress on Pseudomonas fluorescens SBW25 motility and biofilm growth. Using a rectangular-section microfluidic channel under laminar flow, we compared top and bottom surfaces, where gravity either pulls bacteria away or pushes them toward the surface. Results revealed an asymmetric bacterial distribution, leading to varying surface cell densities and contamination levels. We also analyzed spatial reorganization over time and classified bacterial motility under flow. Findings show that external mechanical stresses influence both motility and biofilm morphology, impacting biocontamination patterns based on shear stress and gravity direction. This study provides insights into biofilm control strategies in diverse environments.
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Registered trials
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