Evidence map›Paper›PMID 40595590›Full record

ArticleNature communications2025

Mammalian tRNA acetylation determines translation efficiency and tRNA quality control.

Na Liu, Bingxue Liu, Chun-Rui Ma, Zixin Cai, Jin-Tao Wang, Zi-Qing Chai, Nanlin Zhu, Ting Shao, Yue-Lei Chen, Yu Lin and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. The regulation, function and disease relevance of cytoplasmic tRNAs.Nature reviews. Molecular cell biology · 2026
    Review
  3. Review
  4. tRNAs at the Virus-Host Interface.Wiley interdisciplinary reviews. RNA
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Na Liu *State Key Laboratory of RNA Innovation, Science and Engineering, CAS center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0001-7080-9209
Bingxue Liu *Bioinformatics Center, College of Biology, Hunan University, Changsha, China.
Chun-Rui Ma *State Key Laboratory of RNA Innovation, Science and Engineering, CAS center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Zixin CaiBioinformatics Center, College of Biology, Hunan University, Changsha, China.
Jin-Tao WangKey Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.
Zi-Qing ChaiKey Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, China.
Nanlin ZhuCore Facility of Molecular Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Ting ShaoCell Bank/Stem Cell Bank, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Yue-Lei ChenCell Bank/Stem Cell Bank, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, Shanghai, China.
Yu LinInternational Peace Maternity & Child Health Hospital, Shanghai Key Laboratory of Embryo Original Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. linyu89@mail.ustc.edu.cn.
Yirong WangBioinformatics Center, College of Biology, Hunan University, Changsha, China. wangyirong@hnu.edu.cn.ORCID http://orcid.org/0000-0002-1995-2728
Hong XuInternational Peace Maternity & Child Health Hospital, Shanghai Key Laboratory of Embryo Original Diseases, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. xuhong1168@126.com.ORCID http://orcid.org/0000-0003-0314-9145
Xiao-Long ZhouState Key Laboratory of RNA Innovation, Science and Engineering, CAS center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. xlzhou@sibcb.ac.cn.ORCID http://orcid.org/0000-0002-3701-5965

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32271300
6 · The paper itself

Abstract

Acetylation is a conserved and pivotal RNA modification. Acetylation of tRNA occurs at C12 (ac

Indexed as

Protein BiosynthesisRNA, TransferAcetylationAnimalsHeat-Shock ResponseHumansMiceNIH 3T3 CellsRNA StabilityRNA, Transfer

Identifiers

PMID40595590
PMCPMC12215905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.